TRNA1Val (adenine37-N6)-methyltransferase (EC 2.1.1.223, YfiC) is an enzyme with systematic name S-adenosyl-L-methionine:tRNA1Val (adenine37-N6)-methyltransferase.[1] This enzyme catalyses the following chemical reaction
| TRNA1Val (adenine37-N6)-methyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.223 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- S-adenosyl-L-methionine + adenine37 in tRNA1Val S-adenosyl-L-homocysteine + N6-methyladenine37 in tRNA1Val
The enzyme specifically methylates adenine37 in tRNA1Val (anticodon cmo5UAC).
References
edit- ^ Golovina AY, Sergiev PV, Golovin AV, Serebryakova MV, Demina I, Govorun VM, Dontsova OA (June 2009). "The yfiC gene of E. coli encodes an adenine-N6 methyltransferase that specifically modifies A37 of tRNA1Val(cmo5UAC)". RNA. 15 (6): 1134–41. doi:10.1261/rna.1494409. PMC 2685529. PMID 19383770.
External links
edit- TRNA1Val+(adenine37-N6)-methyltransferase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
