TSPAN14

Tetraspanin 14 is a protein that in humans is encoded by the TSPAN14 gene.

TSPAN14
Identifiers
Aliases	TSPAN14, DC-TM4F2, TM4SF14, tetraspanin 14
External IDs	MGI: 1196325; HomoloGene: 23717; GeneCards: TSPAN14; OMA:TSPAN14 - orthologs
Gene location (Human) Chr. Chromosome 10 (human) Band 10q23.1 Start 80,454,166 bp End 80,533,124 bp
Gene location (Mouse) Chr. Chromosome 14 (mouse) Band 14 B|14 22.36 cM Start 40,628,402 bp End 40,688,764 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lung granulocyte tibial nerve upper lobe of left lung monocyte subcutaneous adipose tissue skin of leg skin of abdomen apex of heart ganglionic eminence Top expressed in decidua primary oocyte granulocyte gastrula stroma of bone marrow transitional epithelium of urinary bladder secondary oocyte lens right kidney molar More reference expression data BioGPS n/a
Gene ontology Molecular function enzyme binding Cellular component integral component of membrane integral component of plasma membrane membrane plasma membrane specific granule membrane tertiary granule membrane cell surface tetraspanin-enriched microdomain endoplasmic reticulum lumen Biological process positive regulation of Notch signaling pathway neutrophil degranulation protein localization to plasma membrane protein maturation cell surface receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 81619 52588 Ensembl ENSG00000108219 ENSMUSG00000037824 UniProt Q8NG11 Q8QZY6 RefSeq (mRNA) NM_001128309 NM_030927 NM_001351266 NM_001351267 NM_001351268 NM_001351269 NM_001351270 NM_001351271 NM_001351272 NM_145928 NM_001316748 RefSeq (protein) NP_001121781 NP_112189 NP_001338195 NP_001338196 NP_001338197 NP_001338198 NP_001338199 NP_001338200 NP_001338201 NP_001303677 NP_666040 Location (UCSC) Chr 10: 80.45 – 80.53 Mb Chr 14: 40.63 – 40.69 Mb PubMed search
Wikidata
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Further reading

• Bankovic J, Stojsic J, Jovanovic D, Andjelkovic T, Milinkovic V, Ruzdijic S, Tanic N (February 2010). "Identification of genes associated with non-small-cell lung cancer promotion and progression". Lung Cancer. 67 (2): 151–9. doi:10.1016/j.lungcan.2009.04.010. PMID 19473719.