TSPYL1

Testis-specific Y-encoded-like protein 1 is a protein that in humans is encoded by the TSPYL1 gene.

TSPYL1
Identifiers
Aliases	TSPYL1, TSPYL, TSPY-like 1, TSPY like 1
External IDs	OMIM: 604714; MGI: 1298395; HomoloGene: 22522; GeneCards: TSPYL1; OMA:TSPYL1 - orthologs
Gene location (Human) Chr. Chromosome 6 (human) Band 6q22.1 Start 116,267,760 bp End 116,279,930 bp
Gene location (Mouse) Chr. Chromosome 10 (mouse) Band 10|10 B1 Start 34,158,186 bp End 34,161,271 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in germinal epithelium lateral nuclear group of thalamus Pons Brodmann area 23 pars compacta seminal vesicula external globus pallidus superior vestibular nucleus Parietal Lobe Skeletal muscle tissue of rectus abdominis Top expressed in ventral tegmental area habenula dorsomedial hypothalamic nucleus pontine nuclei lateral hypothalamus globus pallidus Gonadal ridge paraventricular nucleus of hypothalamus median eminence arcuate nucleus More reference expression data BioGPS More reference expression data
Gene ontology Molecular function enzyme binding Cellular component nucleus nucleolus Biological process nucleosome assembly biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7259 22110 Ensembl ENSG00000189241 ENSMUSG00000047514 UniProt Q9H0U9 O88852 RefSeq (mRNA) NM_003309 NM_009433 RefSeq (protein) NP_003300 NP_033459 Location (UCSC) Chr 6: 116.27 – 116.28 Mb Chr 10: 34.16 – 34.16 Mb PubMed search
Wikidata
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Further reading

• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Scherl A, Couté Y, Déon C, et al. (2003). "Functional proteomic analysis of human nucleolus". Mol. Biol. Cell. 13 (11): 4100–9. doi:10.1091/mbc.E02-05-0271. PMC 133617. PMID 12429849.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Puffenberger EG, Hu-Lince D, Parod JM, et al. (2004). "Mapping of sudden infant death with dysgenesis of the testes syndrome (SIDDT) by a SNP genome scan and identification of TSPYL loss of function". Proc. Natl. Acad. Sci. U.S.A. 101 (32): 11689–94. Bibcode:2004PNAS..10111689P. doi:10.1073/pnas.0401194101. PMC 511011. PMID 15273283.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• de Andrade TG, Peterson KR, Cunha AF, et al. (2006). "Identification of novel candidate genes for globin regulation in erythroid cells containing large deletions of the human beta-globin gene cluster". Blood Cells Mol. Dis. 37 (2): 82–90. doi:10.1016/j.bcmd.2006.07.003. PMID 16952470.