Tabernamine is a bisindole isolate of Tabernaemontana with anticancer activity.[1]
Identifiers | |
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ChemSpider | |
PubChem CID
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Properties | |
C40H48N4O2 | |
Molar mass | 616.850 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Derivatives
edit19,20-dihydrotabernamine is said to have potent acetylcholinesterase inhibitor activity greater than galantamine.
Notes
edit- ^ Nge, Choy-Eng; Chong, Kam-Weng; Thomas, Noel F.; Lim, Siew-Huah; Low, Yun-Yee; Kam, Toh-Seok (2016). "Ibogan, aspidosperman, vincamine, and bisindole alkaloids from a Malayan Tabernaemontana corymbosa: Iboga alkaloids with C-20α substitution". Journal of Natural Products. 79 (5): 1388–1399. doi:10.1021/acs.jnatprod.6b00129. PMID 27077800.
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