Tafsir al-Kabir may refer to:
- Tafsir al-Kabir (al-Razi) by Fakhr al-Din al-Razi, commonly known as Mafatih al-Ghayb
- Tafsir al-Tabari by Ibn Jarir al-Tabari
- Tafseer-e-Kabeer, by Mirza Basheer-ud-Din Mahmood Ahmad
- Tafsir al-Thalabi by Ahmad ibn Muhammad al-Thalabi