Takatsuki may refer to:
- Takatsuki, Osaka, a city in Osaka Prefecture, Japan
- Takatsuki Station (Osaka), a railway station
- Takatsuki, Shiga, a former town in Shiga Prefecture, Japan
- Takatsuki Station (Shiga), a railway station
- Takatsuki-class destroyer, a class of vessels of the Japan Maritime Self-Defense Force
- JDS Takatsuki (DD-164), lead ship of the class