Talk:1-Docosanol

Latest comment: 12 years ago by Kubosu in topic Deletion

Generic Version

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Seeing as Abreva is so costly, I was wondering does anyone know when this drug will go generic? If so that would make a good addition to the aritcle

99.149.195.30 (talk) 14:59, 28 June 2012 (UTC)BetsyReply

CAS number was referencing the correct entry in NLM but not in any chemistry text available, including Merck Index

Merge

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Docosanol and behenyl alcohol are synonyms, so the two articles should be merged. —Preceding unsigned comment added by 70.110.242.53 (talk) 23:18, 17 October 2007 (UTC)Reply

I agree - Alison 23:20, 17 October 2007 (UTC)Reply
 Y Done :) Fvasconcellos (t·c) 23:44, 17 October 2007 (UTC)Reply
Yay!! - Alison 00:05, 18 October 2007 (UTC)Reply


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Link to court case does not work. Replaced link with working link. —Preceding unsigned comment added by 209.102.147.25 (talk) 19:11, 2 September 2008 (UTC)Reply

Unsupported claim concerning efficacy of Docosanol

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The claim that Docosanol "was shown to shorten the [sic] healing by 17.5 hours on average" does not appear to be supported by the reference that follows that statement. In fact, the journal article appears to conclude that "n-docosanol had no effect" and that "n-docosanol showed no benefit." See the full article here: http://archderm.ama-assn.org/cgi/content/full/137/9/1153

I recommend that we either remove this statement altogether or provide the actual findings of the article. (My preference is for the latter). Cak58 (talk) 22:31, 25 July 2011 (UTC)Reply

You link does not point to the cited paper, which is here. I can't find a free full text at the moment. However, your link shows that there are published negative trials, contrary to what the article claims. --ἀνυπόδητος (talk) 06:28, 26 July 2011 (UTC)Reply
After actually reading the study you cited: It was done in guinea pigs, so it is hardly relevant for a marketed drug for which phase III studies are available. I suppose the sentence "Three other trials showed negative results, but these were not published" has to be enough unless they are somewhere on the internet we could link to. --ἀνυπόδητος (talk) 14:25, 26 July 2011 (UTC)Reply

My mistake. I'm not sure how I got those articles mixed up. I will continue digging, however, and if I find anything I'll post the information here. Cak58 (talk) 18:13, 26 July 2011 (UTC)Reply

Thanks for keeping your eyes open! --ἀνυπόδητος (talk) 08:51, 27 July 2011 (UTC)Reply

Deletion

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I deleted line "If headaches develop while using the ointment, one is recommended to take an over-the-counter medication such as paracetamol to alleviate the pain." Why does this give directives to administer a drug, although this is a direct contradiction to the first statement in the Contraindications section. Is Wikipedia a doctor? Do we have a patient history? If you look at source 13 this section is almost plagiarized to top it all off. The livestrong article is based on a Mayo Clinic page that says nothing about taking medication for headaches resulting from docosanols use. On another note those are some pretty scary side effects for an over the counter topical medication... I like the vague Mechanisms of Action — Preceding unsigned comment added by Kubosu (talkcontribs) 07:27, 1 November 2012 (UTC)Reply

Thanks, you are perfectly right in deleting that. Wikipedia is not a manual. I think I'm going to delete some more.
I'm under the impression that no one really knows the mechanism, or whether there is a mechanism at all... --ἀνυπόδητος (talk) 09:29, 1 November 2012 (UTC)Reply
Thank you for the warm welcome. I was reading the article and that just jumped out at me as pretty egregious. Kubosu (talk) 18:47, 1 November 2012 (UTC)Reply