Talk:2,6-Xylidine

Inconsistant data on melting point.

This page has an mp of ~11.4. The generalized xylidine has an mp of 8.4 for the 2,6 isomer.

unsourced

moved here per WP:PRESERVE. Per WP:BURDEN please do not restore without finding reliable sources, checking the content against them, and citing them.

Drug uses

2,6-Xylidine is used in the production of a slew of pharmaceutical drugs. For Example:

1. Droxicainide
2. Etidocaine
3. Lidamidine
4. Lidocaine (Lignocaine)
5. Lidofenin
6. Lidoflazine
7. Nefiracetam
8. Pincainide
9. Ranolazine
10. Tocainide
11. Mepivacaine
12. Bupivacaine
13. Ropivacaine

A lot of these can be grouped as local anesthetics. The rationale behind using the ortho-dimethylated aniline design is to shield the molecule from enzymes that metabolize the drug by amide degradation.

-- Jytdog (talk) 20:37, 11 April 2017 (UTC)

unsourced 2

moved here per PRESERVE

Drug uses

2,6-Xylidine is used in the production of some pharmaceutical drugs, including:

1. Ameltolide
2. Bupivacaine
3. Butanilicaine
4. Droxicainide
5. Etidocaine
6. Lidamidine
7. Lidocaine (Lignocaine)
8. Lidofenin
9. Lidoflazine
10. Mepivacaine
11. Nefiracetam
12. Neraminol
13. Pilsicainide
14. Pincainide
15. Pyrrocaine
16. Ralitoline
17. Ranolazine
18. Recainam
19. Rodocaine
20. Ropivacaine
21. Tocainide
22. Transcainide
23. Xilobam
24. Xipamide
25. Xylazine

Many of these are local anesthetics. The rationale behind using the ortho-dimethylated aniline design is to shield the molecule from enzymes that metabolize the drug by amide degradation.

-- Jytdog (talk) 02:32, 21 September 2017 (UTC)