Talk:Autoimmune hemolytic anemia

Latest comment: 12 years ago by Hoganpc in topic Temperature range of cold AIHA?

Update

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I have updated the page so it should no longer be considered a stub.Hoganpc (talk) 15:35, 16 June 2011 (UTC)Reply

Drug

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Drug induced hemolytic anemia

Should this be listed as cold or warm or under a separate sub-heading? Snowman 11:11, 25 March 2006 (UTC)Reply

What is Mixed-type autoimmune hemolytic anemia? Snowman 10:15, 27 March 2006 (UTC)Reply

Recent updates

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Well done to Hoganpc (talk · contribs) for updating the article. Could I recommend that you follow the instructions on WP:MEDMOS how to organise the sections, and possibly add some {{cite journal}} code to the references (e.g. PMID, PMC, DOI). JFW | T@lk 20:23, 16 June 2011 (UTC)Reply

Ok thanks! I'll do that when I get the time.Hoganpc (talk) 19:58, 18 June 2011 (UTC)Reply

Spelling

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The article has recently been significantly expanded by Hoganpc using inconsistent spelling, including a move to autoimmune haemolytic anemia. I have standardized the spelling to American spelling that the stub existed in (albeit inconsistently) prior to this. However, if it had been their intention for the article to be written with non-US spelling—as might be suggested by the hemolytichaemolytic move and the spelling used in the lead—because they are the first major contributor to this article, if Hoganpc indicates here that the intention was for the article to use this variety, I will move the article and change the spelling accordingly. Some standardized rigour (talk) 07:40, 1 July 2011 (UTC)Reply

Thank-you to Some standardized rigour for the corrections. While it had been my original intention to use the non-American spelling it is probably just as well to use American as it follows suit with other, related articles.Hoganpc (talk) 17:37, 10 August 2011 (UTC)Reply

OK, if you're happy for the article to remain as it is, it should remain here at Autoimmune hemolytic anemia and continue to use American spelling. Some standardized rigour (talk) 08:20, 13 August 2011 (UTC)Reply

Temperature range of cold AIHA?

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It says that this occurs at 0-4 degrees celcius....so only when frostbite occurs? I don't have citations, but I'm sure that the temperature range is somewhat more moderate for triggering cold AIHA. — Preceding unsigned comment added by 201.220.15.105 (talk) 17:25, 29 September 2012 (UTC)Reply

You're quite right, in vivo these antibodies act at a higher temperature. However, they are at their highest activity in vitro at 0-4 degrees. For more on this, the paper by Gehrs and Friedberg in the American Journal of Hematology, 2002 (referenced in this article) is a good review and mentions this in the section titled 'Cold Agglutinin Syndrome', subsection 'Laboratory Evaluation'. I'm not an expert on the topic, but this is my understanding. I appreciate the confusion in this article, I'll change the wording in the relevant section when I have time to find an appropriate article with the correct temperature for in vivo activity (I think 20 degrees, but not certain). Or if you've since found one, then please work away :) Hoganpc (talk) 19:19, 4 October 2012 (UTC)Reply