Would it be beneficial to combine Azvudine with other nucleoside analogs, for example Molnupiravir?

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Title: Azvudine is a thymus-homing anti-SARS-CoV-2 drug effective in treating COVID-19 patients

Open Access Published: 06 December 2021

Azvudine (FNC) is a nucleoside analog

Do Azvudine and Molnupiravir affect same nucleosides or different nucleosides? Or maybe they affect different parts of body, Azvudine affects Thymys.

https://en.wikipedia.org/wiki/Molnupiravir

Molnupiravir is metabolized into a ribonucleoside analog that resembles cytidine

91.159.191.87 (talk) 18:06, 22 February 2023 (UTC)Reply

Azvudine wikipedia article has one source that says cytidine:

Liu Y, Liu B, Zhang Y, Peng Y, Huang C, Wang N, et al. (July 2017). "Intestinal absorption mechanisms of 2'-deoxy-2'-β-fluoro-4'-azidocytidine, a cytidine analog for AIDS treatment, and its interaction with P-glycoprotein, multidrug resistance-associated protein 2 and breast cancer resistance protein". European Journal of Pharmaceutical Sciences. 105: 150–158. doi:10.1016/j.ejps.2017.05.009. PMID 28487144. S2CID 4252337.

91.159.187.240 (talk) 07:03, 26 August 2024 (UTC)Reply