Talk:Brain ischemia

Brain ischemia happens during severe opiate overdose

During an opiate overdose low blood pressure and lack of oxygen to the brain slows down blood flow and can causes brain damage by way of brain ischemia. Brain ischemia is a process that happens during an opiate overdose due to the severe respiratory depression that results in lack of oxygen. I believe this info is relevant enough to be added to the article under the "Causes" section. There are many articles out there about how an opiate overdose causes brain damage due to lack of oxygen and thus blood flow to the brain. Will watch page and add info after a long enough talk period. I'm hesitant because I question whether brain ischemia happens due to de-oxygenated blood or if the blood flows fine during an opiate withdrawal and it is only oxygen deprived. Because of the severe low blood pressure I find this doubtful. Will research and become more educated on the subject and will update this page accordingly. Furthermore and questions or comments within this talk regarding this question will be taken into consideration. Thank you. Kledsky (talk) 06:51, 27 July 2019 (UTC)

I

I just want to know exactly what microvascular ischemia is??Girl

Ischemia means lack of blood supply. Microvascular means it involves small blood vessels. WhatamIdoing (talk) 05:58, 22 January 2008 (UTC)

Would it be reasonable and acceptable to unilaterally change the title of this section of Talk from 'I' to 'What is microvascular ischemia'? Or would it require a consensus? Or just not ever to be done by any but the OP (however not-well the topic title had been made)? UnderEducatedGeezer (talk) 23:10, 24 November 2020 (UTC)

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Image

I really need help adding an image to this article. This image is at http://rad.usuhs.edu/medpix/medpix_image.html?imageid=20376. Your help will be greatly appreciated! Thanks, --Saunc2011 (talk) 15:50, 22 March 2009 (UTC)

Citations

The citations that I have placed in with the additions I have made to the article are listed by the number that preceeds them. The citation may be for a whole paragraph of information. Thank you. --Saunc2011 (talk) 20:37, 29 March 2009 (UTC)

Hello

I am now working on this article for my AP biology project. If you have any suggestions or interests in this topic just let me know on my talk page! :-) All of the project information can be located through the banner at the top of this page. Thanks, --Saunc2011 (talk) 02:50, 24 September 2008 (UTC)

List of Potential References

1. "The Pathophysiology of Brain Ischemia" (PDF).
2. "Two flavors of Ischemia".
3. "Brain Ischemia :: drug therapy".
4. "Adventures in the Pathophysiology of Brain Ischemia: Penumbra, Gene Expression, Neuroprotection".
5. "Oxidative stress in brain ischemia".
6. "Brain ischemia and reperfusion: molecular mechanisms of neuronal injury".
7. "Therapeutic modulation of brain temperature: relevance to ischemic brain injury".
8. "Cortical evoked potential and extracellular K+ and H+ at critical levels of brain ischemia".
9. "Experimental models for the investigation of brain ischemia".
10. "Altered gene expression in brain ischemia".
11. "Why do Purkinje cells die so easily after global brain ischemia? Aldolase C, EAAT4, and the cerebellar contribution to posthypoxic myoclonus".
12. "Bedside Detection of Brain Ischemia Using Intracerebral Microdialysis: Subarachnoid Hemorrhage and Delayed Ischemic Deterioration".
13. "Novel Therapeutic Strategy to Treat Brain Ischemia".
14. "Cerebral Iscemia II. The No-Flow Phenomenon".
15. "The role of cerebral ischemia in Alzheimer's disease".
16. "Hypoxia".
17. "Brain ischemia".
18. "brain ischemia".
19. "Ischemic and Hemorrhagic".
20. "Quantifying Ischemic Damage for Cryonics Rescue".
21. "Focus on Ischemia" (PDF).
22. "What is a stroke?".
23. "What is stroke?".
24. "What is brain death?".
25. "Brain Ischemia".
26. "Stroke".
27. "What is moyamoya disease?".
28. "Brain Ischemia".
29. "The Treatment of Brain Ischemia With Vasopressor Drugs" (PDF).
30. "Ischemic Stroke".
31. "New Way to Protect Brain From Stroke Damage".
32. "Posttraumatic Intracranial Hypertension: Scope of the Problem".
33. "Cerebral ischemia and inflammation".
34. "Cerebral Ischemia".
35. "New Concepts in Cerebral Ischemia".
36. "Ischemic Stroke — The Dana Guide".
37. "The Blood Supply of the Brain".
38. "Cerebral ischemia revisited: New insites as revealed using in vitro brain slice preparations".
39. "Patients unfamiliar with stroke symptoms".
40. "Characterization of vascular protein expression patterns in cerebral ischemia/reperfusion using laser capture microdissection and ICAT-nanoLC-MS/MS".
41. "Transient cerebral ischemia induces delayed proapoptotic Bad translocation to mitochondria in CA1 sector of hippocampus".

• • Very tough finding 40! There's a lot of information though on most of the first 15 to 20. Hopefully, as the project progresses and I learn more about the topic I will find other matters to incorporate, resulting in more references. :-) --Saunc2011 (talk) 00:21, 26 September 2008 (UTC)

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Graded --JimmyButler (talk) 21:36, 27 September 2008 (UTC)

Suggestions

Just a few things I noted while I was glancing through -- random things you'll probably get hit with upon GAN:

• From Background: I, personally, would put the different types of ischemia in the Related conditions section.

• Try to incorporate your See also section into the article itself

• The infobox could use some expanding, and yes, a picture would be great here, but isn't absolutely necessary

• Diagnosis section would be a nice addition

Feel free to drop by at my talk page if you need anything. Cheers! Strombollii (talk) 16:25, 30 March 2009 (UTC)

Also, should the image that you have in your infobox, from the stroke page, be at the top of the article? It seems to be specifically describing Focal ischemia. Strombollii (talk) 12:31, 2 April 2009 (UTC)

• Your Causes section discusses the results of brain ischemia. This would be better placed under a heading such as Prognosis or integrated with Pathophysiology (check with medmos/the doc's mess on that one).

• The information under Management needs sources.

• Really, I prefer Treatment to Management, as "Management" implies the results of living with ischemia: i.e. therapy, rehabilitation as a result of the stroke. But hey, that's more of a stylistic preference

• Prevention section seems viable, given the causes, but that may be a mis-observation.

Strombollii (talk) 04:02, 23 April 2009 (UTC)

Removed ref. from article

• Chang, Steven; Doty, James; Skirboll, Stephen; Steinberg, Gary. Cerebral ischemia . cgi.stanford.edu. URL last accessed February 26 2006.
• Ramirez, Robert; Gulli, Laith. Encyclopedia of Neurological Disorders: Hypoxia. health.enotes.com. URL last accessed February 26 2006. (PDF format)

These two references didn't appear to be be used in the actual article. (If I remember correctly, they were there before the re-write?) Since they aren't foot-noted there really isn't a reason for them to be in the text. Someone might want to put them in some sort of "see also" section? --Yohmom (talk) 19:44, 30 March 2009 (UTC)

Brain ischemia

This article is unclear and needs to be better structured. It is about the the global classification that involves regional ischemia ( TIAs, and ischemic strokes ) and globals ischemias ( secondary to hypotensives crises )--Doc James (talk · contribs · email) 05:36, 5 April 2009 (UTC) Here is one classification system from UPTODATE BRAIN ISCHEMIA

1. Thrombosis
   1. Large vessel disease
   2. Small vessel disease

1. Embolism
   1. High-risk cardiac source
   2. Potential cardiac source
   3. Aortic atherosclerosis

1. Systemic hypoperfusion

1. Blood disorders
2. TOAST classification

--Doc James (talk · contribs · email) 05:37, 5 April 2009 (UTC)

Brain ischemia can be devided into three different groups: thrombosis, emobolism, and hypoperfusion. Each one of these than has a number of causes Embolism can occur due to atrial fib, infectious endocarditis etc, thrombosis can occur in large or small vessels secondary to diabetese and age. Systemic hypoperfusion occurs with MI, with sepsis. --Doc James (talk · contribs · email) 00:16, 6 April 2009 (UTC)

On further reading brain ischemia is a subtype of stroke along with Intracerebral hemorrhage and Subarachnoid hemorrhage.--Doc James (talk · contribs · email) 00:20, 6 April 2009 (UTC)

Organized

Organized this article but a lot more work needs to be done.--Doc James (talk · contribs · email) 19:22, 5 April 2009 (UTC)

WP: MEDMOS doesn't account for a Background section: the info you have could maybe be categorized under Pathophysiology? Strombollii (talk) 12:51, 22 April 2009 (UTC)

Grandfather

is it too serious?? my grand father suffers from brain ischemia. docters said that there is insufficient supply of blood to brain. and there is a clot part in brain. he is like 76 year old,has obesity,is like height of 6 feet.pleasetry to answer. — Preceding unsigned comment added by 14.99.12.253 (talk) 19:39, 9 June 2011 (UTC)

I'm sorry, Wikipedia editors are volunteers who don't necessarily have any medical credentials, and we are not permitted to answer questions about specific cases. You will have to look elsewhere for information. Looie496 (talk) 22:37, 9 June 2011 (UTC)

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Link works. Dhtwiki (talk) 07:23, 2 December 2016 (UTC)

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Merger proposal

The following discussion is closed. Please do not modify it. Subsequent comments should be made in a new section. A summary of the conclusions reached follows.

To not merge, but to reorganize to separate content. Klbrain (talk) 18:29, 14 July 2019 (UTC)

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I propose that Cerebral infarction be merged here. I realize that cerebral infarction is one cause of brain ischemia is a cause of cerebral infarction and they are different with respect to cause/effect, but the content almost completely overlaps when one gets into the details of symptoms, treatment, epidemiology, etc. The other page was created in Nov 2005 as a redirect to Stroke; a bunch of content was added in Feb 2009 and it grew from there. This page was created in Feb 2006 as a stub and grew from there. This page is better sourced, a slightly higher level, better integrated with the rest of WP, and we should merge here. Jytdog (talk) 13:49, 19 June 2018 (UTC) (yep fixed Jytdog (talk) 18:31, 19 June 2018 (UTC))

Strongly disagree. Despite what you've said, I'm not seeing the rationale for a merger; in fact, some of what you've stated here is factually incorrect. Cerebral infarction is caused *by* brain ischemia. See infarction for clarification. The distinction is not pedantic, it's critical. Besides, brain ischemia and brain infarction are absolutely not synonymous; brain ischemia is a complex, multifactorial process with infarction as one of a number of sequelae. Since ischemia causes infarction, one could (wrongly) argue that *any* article about a pathophysiologic process and its results could be combined; for example, why not combine ischemia with myocardial infarction? One major reason why there should *not* be a merger is the fact that brain ischemia underlies *many* different disease states including stroke and (importantly) cardiac arrest. For example, my own focus as someone in the medical field is in brain ischemia as it pertains to cardiac arrest (and NOT cerebral infarction per se). I maintain that the difference is substantial enough (between a complex process and one of its results) that there should not be a merger. FWIW, if there were to be a merger, it would make much more sense to merge with ischemia (though I am not arguing in favor of such). Global Cerebral Ischemia (talk) 17:03, 19 June 2018 (UTC)

Yeah OK you are right that I got that backwards. Thanks for pointing that out. What is not correct about what you write, is how the pages have come to overlap each other. Please look at them. This is what tends to happen, here in WP. Pages like this tend to get blurred together over time. It is part of what we have to think about here in WP when we think about maintaining pages over the long term. Jytdog (talk) 18:31, 19 June 2018 (UTC)

Strongly oppose merging. Even if the pages are perceived to be "blurred", the solution is to reorganize them to focus better on their respective, fundamentally distinct topics. Merging the articles makes the problem worse, not better. Indeed, it ensures continued confusion, by allowing the "blurring", rather than the conceptually distinct topics, to determine which articles should exist and where content should be placed. In effect, merger endorses the "blurring".

—Syrenka V (talk) 11:08, 3 January 2019 (UTC)

The discussion above is closed. Please do not modify it. Subsequent comments should be made on the appropriate discussion page. No further edits should be made to this discussion.

Role of NOX4 enzyme?

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699031/

Very interesting paper.

Mfernflower (talk) 01:37, 10 April 2021 (UTC)

Awkward Grammar

"The interruption of blood flow to the brain for ten seconds results in the immediate loss of consciousness."

This is awkward. "The interruption of blood flow to the brain for about ten seconds results in loss of consciousness" would be better. The loss of consciousness is not immediate. It happens after 10 seconds. The subject of the sentence is "interruption," so that's the time base that applies for the remainder of the sentence. Adding "immediate" only introduces an unresolvable temporal conflict within the sentence. Also, "about" should be used to describe the time interval because that time is not the same for everyone. I will check back in a week, and absent any disagreement or discussion, I'll change it. — Preceding unsigned comment added by 69.132.234.128 (talk) 20:31, 29 April 2022 (UTC)

Wiki Education assignment: Cardiopulmonary and Diagnostic Applications 1

This article was the subject of a Wiki Education Foundation-supported course assignment, between 16 January 2024 and 3 May 2024. Further details are available on the course page. Student editor(s): 1w1q1 (article contribs).

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