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i'm not sure how to add references, but here are some that discuss the proinflamatory pathway
1. Tracey, K. J. et al. Shock and tissue injury induced by recombinant human cachectin. Science 234, 470± 474 (1986). 2. Dinarello, C. A. The interleukin-1 family: 10 years of discovery. FASEB J. 8, 1314±1325 (1994). 3. Wang, H. et al. HMG-1 as a late mediator of endotoxin lethality in mice. Science 285, 248±251 (1999). 4. Nathan, C. F. Secretory products of macrophages. J. Clin. Invest. 79, 319±326 (1987).
and a great paper on this subject
Borovikova et al. Vagus nerve stimulation attenuates the systemic inflammatory response to endotoxin. Nature (2000)
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