Talk:Collagen, type I, alpha 1

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Some text in this article was originally taken from http://ghr.nlm.nih.gov/gene=col1a1 (public domain)

A rare disease

Latest comment: 6 years ago1 comment1 person in discussion

Reciprocal translocations between chromosomes 22 and 17, at sites where Platelet-derived growth factor subunit B gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor.

The above translocation ,as mentioned, cause a disease due to unregulated growth factor. However I don't now if collagen type I (encoded by the COL1A1 gene) ever affected ?

source: https://en.wikipedia.org/wiki/PDGFB

Yasir muhammed ali (talk) 08:24, 4 April 2018 (UTC)Reply

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