Talk:Creutzfeldt–Jakob disease

Wiki Education Foundation-supported course assignment

This article was the subject of a Wiki Education Foundation-supported course assignment, between 2 September 2020 and 11 December 2020. Further details are available on the course page. Student editor(s): Smaiads.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 18:38, 16 January 2022 (UTC)

It's a mess.

  No cases of health care associated transmission of CJD have been reported subsequent to the adoption of current sterilization procedures, or since 1976.[30][31][32]

Deleted the above. It's contradicted by multiple cites further down in the page.

  Blood products
  As of 2018, evidence suggests that while there may be prions in the blood of individuals with vCJD, this is not the case in individuals with sporadic CJD.[4]

Deleted the above. Even if the cite proves the negative -- it's from 2003, and can't prove a negative a decade and a half into the future.

Came here to see if the exposure of 8 patients of Tulane University Medical Center (Louisiana, USA) had resulted in any contracting the disease. https://www.nola.com/entertainment_life/health_fitness/article_193aa854-6f3f-5db2-88b6-d0abbbc5892c.html Found that reference, but I believe the article is misdated.

I know not everyone has English as a first (or second, or third) language, but the language is a mess -- the terminology for the subject of the page itself isn't consistent. IE iatrogenic CKD -- I believe that would be vCKD; iatrogenic is how the disease was acquired, not what it is.

KV — Preceding undated comment added 15:54, 5 December 2021 (UTC)

Direct contradiction?

From the introduction:

  There is no evidence that it can spread between people via normal contact or blood transfusions.[2] 

From the Transmission section:

  The defective protein can be transmitted by contaminated harvested human brain products, as well as blood transfusions.[16]

Correct me if I'm wrong, but aren't these two directly contradictory? Can it be spread via blood transfusions or not? This would appear to be a pretty important point to get right. 66.45.130.164 (talk) 06:19, 8 August 2017 (UTC)

Thanks. Fixed the source in the body Doc James (talk · contribs · email) 17:09, 8 August 2017 (UTC)

I just removed the intro blanket statement, leaving the Lancet reference to stand for itself in the main body. — Preceding unsigned comment added by 96.92.251.106 (talk) 00:59, 5 June 2018 (UTC)

Image shows vCJD not cCJD

Image shows cells with vCJD ("Biopsy of the tonsil in variant CJD."), but the body of the article is pretty clear that this is a different thing ("Not to be confused with variant Creutzfeldt–Jakob disease." and "CJD is different from bovine spongiform encephalopathy (mad cow disease) and variant Creutzfeldt–Jakob disease (vCJD).") Can the image be replaced or removed to avoid confusion? — Preceding unsigned comment added by Bakerccm (talk • contribs) 15:17, 6 June 2018 (UTC)

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For own work

• Duncan, Emma J.; Cheetham, Michael E.; Chapple, J. Paul; van der Spuy, Jacqueline (2015), Blatch, Gregory Lloyd; Edkins, Adrienne Lesley (eds.), "The Role of HSP70 and Its Co-chaperones in Protein Misfolding, Aggregation and Disease", The Networking of Chaperones by Co-chaperones, vol. 78, Springer International Publishing, pp. 243–273, doi:10.1007/978-3-319-11731-7_12, ISBN 9783319117300, retrieved 2019-06-19
• Stroylova, Y. Y.; Kiselev, G. G.; Schmalhausen, E. V.; Muronetz, V. I. (August 2014). "Prions and chaperones: Friends or foes?". Biochemistry (Moscow). 79 (8): 761–775. doi:10.1134/S0006297914080045. ISSN 0006-2979.

∯WBG^converse 07:30, 19 June 2019 (UTC)

Attention!

A new type of CJD can emerge after a COVID-19 vaccination. — Preceding unsigned comment added by Saprofyt (talk • contribs) 08:31, 20 February 2022 (UTC)

The linked source is a un-peer reviewed article that is hosted online, but does not appear to have been published in any journals. There are a number of red flags in the source that suggest it may not be authentic scientific research, including referring using quotation marks to refer to the "vaccine" to imply it may not be a genuine vaccine. This article is does not meet an appropriate scientific standard to justify the claim that CJD can be caused by mRNA vaccines. — Preceding unsigned comment added by 163.116.194.20 (talk) 23:29, 20 February 2022 (UTC)

References