Talk:DNA adenine methylase

Wiki Education Foundation-supported course assignment

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  This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): Scpathuri. Peer reviewers: Jkenchel.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 18:57, 16 January 2022 (UTC)Reply

Move

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I moved the article from "Dam (methylaze)" to "Dam methylase" because the enzyme seems to be frequently talked about in that way, including in the article. In addition, in my opinion (and I think in Wikipedia's Manual of Style), it is better to have a name without disambiguation in it. If anyone would like to move it back or to give it a different name, leave a message on my talk page (expect a 2 to 5 day wait) or make a page move request. -- Kjkolb (talk) 00:35, 21 July 2013 (UTC)Reply

Suggestions for review

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Overall:

- I see that this has been discussed already, but I feel that the redundancy of "Dam methylase" ("DeoxyriboAdenosine Methylase methylase") should be avoided if possible. Perhaps spelling out its name in the title ("Deoxyriboadenosine methylase"), then referring to it as DAM in the first sentence of the article ("Deoxyriboadenosine methylase (DAM)") would be better. The pages "DAM", "DAM (methylase)", "Dam methylase" etc. could be set to redirect here.

- There are many sentences that are not cited.

- The article seems to focus more around the cellular role of DNA methylation than that of DAM itself. I wonder if this article might be better off integrated into the DNA methylation article, with the aforementioned titles redirecting to that section of that article.

- Try to limit jargon or explain/Wikilink it where possible. Examples include "5'-GATC-3'", MutS/L/H, and "hemimethylated".


Mismatch repair section:

- "immediately" probably shouldn't be italicized, since this is a stylistic choice rather than standard format used for titles, words in other languages, etc.


Replication section:

- Is DAM only found in bacteria? Are the other proteins mentioned (including Mut, etc.) only bacterial? Perhaps that's what sets this article aside from DNA methylation in general, then. If that's the case, it should be stated in the introduction, and possibly elsewhere, that DAM is only found in bacteria.