Talk:Dehydrogenase

Latest comment: 8 years ago by Jessicook in topic outline for proposed edit

Whats is the plural?

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What is the plural? Dehydrogenases? Dehydrogeni? Ahavahisrael (talk) 13:35, 29 September 2014 (UTC)Reply

Proposed Bibliography for edit of page

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I am planning on editing the page to add details about oxidoreductases, the use of NAD+/NADP+, more details on specific examples (alcohol dehydrogenase), and how dehydrogenases are used in the TCA cycle. Here are some of the resources I am planning on using:

1) Voet, Donald, Judith G. Voet, and Charlotte W. Pratt. Fundamentals of Biochemistry: Life at the Molecular Level. New York: Wiley, 2006. Print.

2) Goodsell, D.S. "Alcohol Dehydrogenase". RCSB Protein Data Bank. doi:10.2210/rcsb_pdb/mom_2001_1.

3) Hurley, J. H.; Dean, A. M.; Koshland, D. E.; Stroud, R. M. (1991-09-03). "Catalytic mechanism of NADP(+)-dependent isocitrate dehydrogenase: implications from the structures of magnesium-isocitrate and NADP+ complexes". Biochemistry 30 (35): 8671–8678. ISSN 0006-2960. PMID 1888729.

4) "What are Oxidoreductases?". www.chem.uwec.edu. Retrieved 2016-02-02.

5)"Pyruvate Dehydrogenase & Krebs Cycle". www.rpi.edu. Retrieved 2016-02-02.

6) King, Michael W. (7 January 2016). "Pyruvate Dehydrogenase (PDH) and the TCA Cycle (Krebs cycle)". The Medical Biochemistry Page. Retrieved 1 February 2016.

Jessicook (talk) 03:31, 2 February 2016 (UTC)Reply

outline for proposed edit

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1) define oxidoreductases (using source 4 & 1 from above)

a. distinguish between a dehydrogenase and a reductase

2) In depth description of dehydrogenase

a. Reactions they catalyze

b. How to identify a dehydrogenase

c. What the reaction looks like (with a picture)- using chemdraw

3) Use of cosubstrates (source 1)

a. NAD+/NADP (source 3 & 1)

b. FAD (source 1)

c. When each is used (what type of reactions with examples)

d. How they work

4) Detailed example of a dehydrogenase reaction

a. Either alcohol dehydrogenase or TCA cycle dehydrogenase (source 5,6 or 2) Jessicook (talk) 17:37, 8 February 2016 (UTC)Reply