Talk:Diabetes insipidus

NIH

Much original text for this article was taken from the public domain document "Diabetes Insipidus", NIH Publication No. 01-4620, December 2000, which states: "This e-text is not copyrighted. The clearinghouse encourages users of this e-pub to duplicate and distribute as many copies as desired."

This is a really good article, and in my opinion more articles should follow this example.18:26, 23 April 2006 (UTC)

Desmopressing/dDAVP in dipsogenic DI/primary polydipsia

Walsh's handbook of clinical endocrinology states that small doses of dDAVP may be useful in primary polydipsia. However, this requires close monitoring Oliver Keenan 18:21, 30 January 2006 (UTC)

You aren't kidding close monitoring. I have taken care of one patient in the ICU due to hyponatremic seizures because someone treated polyuria as DI without a water deprivation test. It only took 2 doses. alteripse 02:50, 31 January 2006 (UTC)

Survivor

[1]diagnosed around 16 months but first sick around 10 months old, in 2006 going for 3 years old now and happy/healthy. Another documented case of a tuberculoma causing CDI.--Smkolins 02:32, 12 October 2006 (UTC)

Treatment

Why does nephrogenic DI benefit from use of a diuretic?? rhetoric 14:57, 21 October 2007 (UTC)

I answered my own question if anyone wants to make an addition:

"Hydrochlorothiazide may improve symptoms. This may be used alone or in combination with other medications, including indomethacin. Although this medication is a diuretic (these medications are usually used to increase urine output), in certain cases hydrochlorothiazide can actually reduce urine output for people with nephrogenic DI.

This medication works by causing sodium and water to be excreted in the early part of the renal tubules (the proximal tubules).

This leaves less fluid available for the late portion of the kidney (distal tubule) to excrete -- this is the portion affected by nephrogenic DI -- and thus it limits the total volume of urine that can be excreted."

http://www.nlm.nih.gov/medlineplus/ency/article/000511.htm rhetoric 00:42, 22 October 2007 (UTC)

Does DI have types?

"DI is caused by a deficiency of antidiuretic hormone (ADH), also known as vasopressin, due to the destruction of the back or 'posterior' part of the pituitary gland where vasopressin is normally released from, or by an insensitivity of the kidneys to that hormone."

So let me get this straight: Autoimmune destruction of the pancreas causes type 1 DM, and insulin resistance causes type 2 DM. Likewise, destruction of the posterior pituitary causes central DI, and vasopressin resistance causes nephrogenic DI. Has any reliable source called central DI "type 1" and nephrogenic DI "type 2", drawing an analogy between vasopressin in DI and insulin in DM? --Damian Yerrick (talk | stalk) 21:41, 12 May 2008 (UTC)

Every time I read information on nephrogenic cases the description was the kidney was damaged, not developing resistance.--Smkolins (talk) 06:26, 18 May 2008 (UTC)

Correction of this article

Over the next week or so, I intend to make some edits in this article to make it more clear. I believe at many times, the lines between the different types of DI are blurred where they should not be (for example, DI does not mean that in all cases, the kidney is unable to process ADH). Also, if there are no objections, I intend to change "Cranial" to "Central" for the first type, as I believe that is the most common usage. Cfirst (talk) 22:26, 14 February 2009 (UTC)

Diabetes insipidus and Diabetes mellitus

I added a paragraph in the Introduction section of this article describing the differences between Diabetes Insipidus and Diabetes Mellitus. As both of them are called diabetes, some readers may get confused. The paragraph I added was almost entirely copied from the article Nephrogenic diabetes insipidus. Hope nobody minds... --186.206.74.199 (talk) 00:45, 26 August 2011 (UTC)

Yes that is why I have just added a suggestion here that we have a tag at the start of this article. ACEOREVIVED (talk) 16:26, 29 January 2013 (UTC)

Review

Mostly on diagnosis: doi:10.1210/jc.2012-1981 JFW | T@lk 23:22, 1 September 2012 (UTC)

Add a tag to head this article

I suggest that some one adds a tag heading this article, saying "Not to be confused with diabetes mellitus". I welcome feedback on this suggestion. ACEOREVIVED (talk) 16:25, 29 January 2013 (UTC)

Journal articles

• Robertson, Gary L. "Diabetes insipidus: Differential diagnosis and management." Best Practice & Research Clinical Endocrinology & Metabolism (2016).
• Thompson, C. J., and P. H. Baylis. "Thirst in diabetes insipidus: clinical relevance of quantitative assessment." QJM 65.1 (1987): 853-862.
• Hannon, M. J., et al. "Acute glucocorticoid deficiency and diabetes insipidus are common after acute traumatic brain injury and predict mortality." The Journal of Clinical Endocrinology & Metabolism 98.8 (2013): 3229-3237.
• Fenske, Wiebke, and Bruno Allolio. "Current state and future perspectives in the diagnosis of diabetes insipidus: a clinical review." The Journal of Clinical Endocrinology & Metabolism 97.10 (2012): 3426-3437.
• Di Iorgi, Natascia, et al. "Diabetes insipidus–diagnosis and management." Hormone research in paediatrics 77.2 (2012): 69-84.

--Christian140 (talk) 09:07, 22 April 2016 (UTC)