Talk:Dilute Russell's viper venom time

Latest comment: 5 years ago by Texner43 in topic How the test works

Besides one or more solid references for this article, it would be nice if some history could be added as well (with references): who first devised this test, how, where and when? --Jwinius 20:49, 10 July 2006 (UTC)Reply

How the test works

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OK, lets try to settle down the edit conflicts. The point of this test is that it is a clotting assay which is very dependant on the availability of phospholipid for its activity. Thus, substances which alter the availability of phospholipid to the other clotting factors, most notably lupus anticoagulants, cause a prolongation in clotting in this assay, which can be reversed by adding more phospholipid. I think that's clear from the ref, if not entirely spelled out in a single sentence or paragraph. -RustavoTalk/Contribs 18:39, 4 June 2007 (UTC)Reply

Hi There, This article definitely needs an update since the references are quite old and the "original" multi-step method superceded. I have been involved with this test since its introduction and have added relevant history. I'm not sure that you need a medico for the mechanism section but rather a laboratory scientist who knows how the test works. I'll have ago at that. The section on clinical significance is still OK despite being quite old.Texner43 (talk) 04:28, 13 October 2019 (UTC)Reply