Talk:Endocarditis

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TEE

TEE recommended for patients with prosthetic valves, rated at least "possible IE" by clinical criteria, or complicated IE [paravalvular abscess]; TTE as first test in other patient

Definition of Terms Used in the Modified Duke Criteria for the Diagnosis of Infective EndocarditisMajor criteria

    Blood culture positive for IE 
       Typical microorganisms consistent with IE from 2 separate blood cultures: Viridans streptococci, Streptococcus bovis, HACEK group, Staphylococcus aureus; or community-acquired enterococci in the absence of a primary focus; or 
       Microorganisms consistent with IE from persistently positive blood cultures defined as follows: At least 2 positive cultures of blood samples drawn >12 h apart; or all of 3 or a majority of 4 separate cultures of blood (with first and last sample drawn at least 1 h apart) 
       Single positive blood culture for Coxiella burnetii or anti–phase 1 IgG antibody titer >1:800 
   Evidence of endocardial involvement 
       Echocardiogram positive for IE (TEE recommended for patients with prosthetic valves, rated at least "possible IE" by clinical criteria, or complicated IE [paravalvular abscess]; TTE as first test in other patients) defined as follows: oscillating intracardiac mass on valve or supporting structures, in the path of regurgitant jets, or on implanted material in the absence of an alternative anatomic explanation; or abscess; or new partial dehiscence of prosthetic valve; new valvular regurgitation (worsening or changing or preexisting murmur not sufficient) 

Minor criteria

   Predisposition, predisposing heart condition, or IDU 
   Fever, temperature >38°C 
   Vascular phenomena, major arterial emboli, septic pulmonary infarcts, mycotic aneurysm, intracranial hemorrhage, conjunctival hemorrhages, and Janeway’s lesions 
   Immunologic phenomena: glomerulonephritis, Osler’s nodes, Roth’s spots, and rheumatoid factor 
   Microbiological evidence: positive blood culture but does not meet a major criterion as noted above* or serological evidence of active infection with organism consistent with IE 
   Echocardiographic minor criteria eliminated 

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Modifications shown in boldface.

• Excludes single positive cultures for coagulase-negative staphylococci and organisms that do not cause endocarditis.

TEE indicates transesophageal echocardiography; TTE, transthoracic echocardiography. Reprinted with permission from Clinical Infectious Diseases.35 Copyright 2000, The University of Chicago Press.

Definition of Infective Endocarditis According to the Modified Duke CriteriaDefinite infective endocarditis

   Pathological criteria 
       Microorganisms demonstrated by culture or histological examination of a vegetation, a vegetation that has embolized, or an intracardiac abscess specimen; or 
       Pathological lesions; vegetation or intracardiac abscess confirmed by histological examination showing active endocarditis 
   Clinical criteria 
       2 major criteria; or 
       1 major criterion and 3 minor criteria; or 
       5 minor criteria 
   Possible IE 
       1 major criterion and 1 minor criterion; or 
       3 minor criteria 
   Rejected 
       Firm alternative diagnosis explaining evidence of IE; or 
       Resolution of IE syndrome with antibiotic therapy for <4 days; or 
       No pathological evidence of IE at surgery or autopsy, with antibiotic therapy for <4 days; or 
       Does not meet criteria for possible IE as above 

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Modifications shown in boldface. Reprinted with permission from Clinical Infectious Diseases.35 Copyright 2000, The University of Chicago Press.

Mortality question

What is the likely hood of mortality from this Endocarditis, When there is a mass a deterioration and bone loss of the ribs, Also the mass is near the lung —Preceding unsigned comment added by 67.181.19.144 (talk) 05:49, 27 May 2008 (UTC)

Eagle effect

Penicillins in endocarditis should always be combined with aminoglycosides because of the Eagle effect. Herbbetz (talk) 17:37, 28 June 2008 (UTC)

Bacterial Endocarditis

This should forward to infective endocarditis, not this page. 24.99.86.24 (talk) 22:43, 29 January 2009 (UTC)

suffix "itis"

Hello, I edited (deleted) the commentary about "-itis" being a confusing/uncorrect suffix in the case of NBTE. The commentary said its confusing because NBTE does not involve systemic inflammative response, but its just "itis" not "corporitis" so it can be as small as a needletip and still counts as an inflammation. What do you think? andy602857969@yahoo.com — Preceding unsigned comment added by 94.113.155.18 (talk) 06:47, 22 November 2011 (UTC)

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Is "Etc." ever acceptable?

The intro stops short of listing all the symptoms of endocarditis and just says "etc.". Shouldn't we make a new section and try to put all the signs int here? (perhaps sort into significant and insignificant)? Myoglobin (talk) 23:18, 5 March 2018 (UTC)

Considerations for expanding the article

Hello, I'm considering adding information regarding dental hygiene procedure risk factors, expanding the most common pathogens, and a discussion about culture-negative endocarditis.

I also would like to break out signs and symptoms into their own section with some pictures.

For all the above, I plan on using a few medical textbooks and will find and cite open source when possible. Thanks all! Hbultra (talk) 21:25, 31 July 2019 (UTC)