Talk:Environmental toxicants and fetal development

Cleanup

Cleaned up references, made footnotes, sectionned, some grammar. Really needs an expert, not cleanup. - FrancisTyers 01:14, 30 December 2005 (UTC)

Toxin

Toxins are poisons produced by biological organisms. Please change the use of toxins to something like "Toxic Materials." Lead is not a toxin; it is a toxic material.

Merrium Webster's definition: Main Entry: tox·in Pronunciation: \ˈtäk-sən\ Function: noun Etymology: International Scientific Vocabulary Date: 1886

a poisonous substance that is a specific product of the metabolic activities of a living organism and is usually very unstable, notably toxic when introduced into the tissues, and typically capable of inducing antibody formation

Kevin CBRN Defense (talk) 18:49, 11 September 2009 (UTC)

PTFE

I suggest you include teflon with environmental toxins. see: http://abcnews.go.com/2020/story?id=124363

Arydberg (talk) 18:00, 1 May 2013 (UTC)

Text was not found in reference

I moved the following table to here, because the reference implies that it covers the entire table, but I don't find a corresponding table in the source article. Before insertion, I'd like an explanation regarding how the reference can support the text. Mikael Häggström (talk) 11:55, 26 October 2013 (UTC)

Developmental endpoints vulnerable to environmental disruption

Category	Description and comment
Growth	Growth in all its manifestations (body size, birth weight and rate of growth) is sensitive to environmental insults. While growth is sensitive, it is not specific to environmental exposures, because many factors influence growth, including; genetic, nutrition, maternal disease, tobacco smoke, alcohol, maternal education and socioeconomic status. In characterizing fetal and neonatal growth special attention needs to be given to gestational and postnatal age.
Functional abnormality	Functional abnormalities, typically identified after birth, may be a consequence of environmental exposure prior to or during pregnancy. Neurodevelopmental impairment resulting from prenatal lead exposures represents an example. Either paternal or maternal lead exposure increases the risk of spontaneous abortion and impairs fetal growth and postnatal neurodevelopment. Because maternal bone lead is mobilized during pregnancy, exposures producing abnormal fetal development may have occurred many years prior to the pregnancy. Other functional abnormalities are included in the emerging literature on developmental origins of health and disease.
Structural abnormality	Traditional concern about exposures in pregnancy has focused on birth defects or structural abnormalities. There are ∼50 chemicals, ∼15 infectious agents and several physical agents known to produce human structural malformations.
Death	A common developmental consequence of a chromosomal or genetic abnormality is embryonic, fetal or neonatal death. There are data suggesting an association between certain paternal occupations and increased risk of mortality. Additionally, there are data linking a variety of environmental exposures with embryonic, fetal and neonatal mortality.
Gestational length	Prematurity has not been a traditional developmental endpoint, however, given the increasing evidence that it is susceptible to environmental exposures, the life-long consequences of prematurity, and the persistence of prematurity as a public health problem it will also be considered as an endpoint of abnormal development in this review.

• Reference: Lanphear, Bruce P.; Vorhees, Charles V.; Bellinger, David C. (2005). "Protecting Children from Environmental Toxins". PLoS Medicine 2 (3): e61. doi:10.1371/journal.pmed.0020061. PMC 1069659. PMID 15783252.

Reverted move

Hi Mikael, you did a great job with this article! However, you moved it without discussion and thus without consensus. And I oppose a move. Environmental toxins in pregnancy puts the emphasis on the mother - the one who is pregnant, and not on the fetus. Also women are at higher risks during pregnancy, for instance, smoking can cause premature rupture of the membranes. However, the article is not about the women during pregnancy, it is about the fetus during fetal development. However, the title is a bit clumsy, so if you would like to move the article for instance to Environmental toxins during fetal development, that would be fine with me. Kind regards! Lova Falk talk 20:16, 5 November 2013 (UTC)

Thank you for your input. I've started a discussion about the subject below so that we can hopefully reach a consensus about what to do. Mikael Häggström (talk) 05:29, 6 November 2013 (UTC)

Move to "Environmental toxins in pregnancy"

Environmental toxins and fetal development → Environmental toxins in pregnancy – This article is about effects both on embryogenesis and fetal development, and should therefore have a title of a broader scope. I did get feedback above that use of pregnancy may put the emphasis on the mother, but I think it does much less so than e.g. "maternal exposure to environmental toxins" which is also frequently used. Also, the mother is involved in the subject, such as in having the main power to prevent exposure to environmental toxins as described in the #Avoiding environmental toxins in pregnancy section. Mikael Häggström (talk) 05:24, 6 November 2013 (UTC) Mikael Häggström (talk) 05:24, 6 November 2013 (UTC)

• Oppose this article seems to be talking about teratogens, so relating to foetal development would be more accurate. I do however think that this article and developmental toxicity should be merged with teratology at a later date, as they relate to the same topic. LT910001 (talk) 22:23, 8 November 2013 (UTC)

In recent edits I tried to make it clear that there are multiple pregnancy end-points that are relevant, as also seen in the section on individual substances and toxin classes, and Structural congenital abnormality (which is tied to the scope of teratology) is only one of those pregnancy end-points. Mikael Häggström (talk) 07:21, 9 November 2013 (UTC)

• Oppose because the article is mainly about foetal development. And I must confess that I don't quite grasp the term "pregnancy end-point" so I cannot address your latest comment Mikael. Lova Falk talk 11:10, 10 November 2013 (UTC)

A "pregnancy end-point" is about the same as "an effect on pregnancy", and I see that the corresponding section in the article has been changed to "Effects" for easier reading. In any case, I get your points, and I find it acceptable to keep the article under the "Environmental toxins and fetal development" title. Mikael Häggström (talk) 11:29, 10 November 2013 (UTC)

Effects on various pregnancy end-points

Thank you Mikael Häggström, but now I wonder about this first sentence of the section Effects: Environmental toxins can be described separately by what effects they have on various pregnancy end-points -meaning: ... described by what effects they have on various effects on pregnancy?? Shouldn't it just be: .. described by which effects they have on pregnancy? Lova Falk talk 20:21, 10 November 2013 (UTC)

I fully agree that mentioning "effects" is enough, especially since examples follow that sentence to make its meaning even more clear. I've shortened it down now. Mikael Häggström (talk) 04:54, 11 November 2013 (UTC)

environmental toxicants , not environmental toxins

suggest to change the title given the misuse of the term toxin-- see toxicant.--Wuerzele (talk) 05:11, 16 April 2014 (UTC)

 Done, including dixing double redirects to here. Mikael Häggström (talk) 09:07, 16 April 2014 (UTC)

User:Mikael Häggström|Mikael Häggström]] thank you !--Wuerzele (talk) 21:23, 16 April 2014 (UTC)

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Wiki Education assignment: Developmental and Molecular Biology Spring 2024

This article was the subject of a Wiki Education Foundation-supported course assignment, between 8 January 2024 and 24 April 2024. Further details are available on the course page. Student editor(s): Emilyflint (article contribs).

— Assignment last updated by Dvassallo2020 (talk) 02:44, 8 April 2024 (UTC)