Talk:Epigenetics of anxiety and stress–related disorders

Note

This page needs a bunch of work to clear out primary sources and anchor this more clearly in the reality of experimental science and the difficulties of translating any of this to medicine. It is a great start but also needs a lot of work. Jytdog (talk) 17:51, 11 May 2018 (UTC)

This page has a lot of great detail and was hoping to add these or get feedback on these articles as additional citations.

1. Allison M Burns, Johannes Gräff, Cognitive epigenetic priming: leveraging histone acetylation for memory amelioration, Current Opinion in Neurobiology, Volume 67, 2021, Pages 75-84, ISSN 0959-4388, https://doi.org/10.1016/j.conb.2020.08.011. Most significantly, epigenetic changes and their effects on memory formation are not noted in the article and in recent years, have published many findings as found in the article below. The article notes the changes in neural differentiation as a person ages and details how therapeutic changes will "ameliorate neural decline during normal aging."

2. Birgitta Mc Ewen, Epigenetics and learning, Trends in Neuroscience and Education, Volume 4, Issue 4, 2015, Pages 108-111, ISSN 2211-9493, https://doi.org/10.1016/j.tine.2015.11.002 This article mentions the effects of early exposure to stress that can impact learning capabilities.

3. Delgado-Morales, Raúl et al. “Epigenetic mechanisms during aging and neurogenesis as novel therapeutic avenues in human brain disorders.” Clinical epigenetics vol. 9 67. 29 Jun. 2017, doi:10.1186/s13148-017-0365-z Most significantly, epigenetic changes and their changing effects with age is not noted in the article. This article states that many neurological degenerative diseases are associated with dysfunctioning epigenetic patterns, in particular changes in acetylation and modeling patterns due to aging effects.

Proposed merge

Transgenerational stress inheritance seems to overlap this article a lot. I think merging would make reading and maintenance easier, though I'm agnostic as to the title. We also have a lot of closely related articles, like Transgenerational epigenetic inheritance and Transgenerational trauma, and this merge would cut down on the navigational maze a bit. -- Beland (talk) 18:24, 22 March 2022 (UTC)

• Support this merge. Joyous! | Talk 05:34, 22 November 2022 (UTC)
• Oppose, firstly because the direction doesn't make sense, as Transgenerational stress inheritance is a broader topic, while Epigenetics of anxiety and stress–related disorders is a subset which describes the most likely mechanism. We already have the articles in SUMMARY format, with the Transgenerational stress inheritance#Mechanism being a summary of the other page. My view is that a merge to Transgenerational stress inheritance would unbalance the page, focussing too much on the mechnanism and not enough on the phenomenon more broadly. My view is that the current structure works sufficiently well for readers. Klbrain (talk) 13:49, 16 March 2023 (UTC)
• Support per nomination. Epigenetic mechanisms are the only ones proposed in the inheritance article and can be combined into one. Should the new article become to big or unbalanced, I'd support splitting the biochemistry and molecular genetics. --89.206.112.10 (talk) 17:02, 4 May 2023 (UTC)

  Y Merger complete. Klbrain (talk) 08:01, 18 June 2023 (UTC)

Wiki Education assignment: EPIGENETICS

This article was the subject of a Wiki Education Foundation-supported course assignment, between 19 January 2022 and 17 May 2022. Further details are available on the course page. Student editor(s): Prikale (article contribs). Joyous! | Talk 05:36, 22 November 2022 (UTC)

Wiki Education assignment: Comparative Developmental Biology

This article was the subject of a Wiki Education Foundation-supported course assignment, between 8 January 2024 and 19 April 2024. Further details are available on the course page. Student editor(s): Nasyed9, Kswoolen, Analyticace, Madisonyuying (article contribs). Peer reviewers: Najjar123, Kannbrown2, Ddav4, UabBG26.

— Assignment last updated by Ddav4 (talk) 05:27, 19 February 2024 (UTC)