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This article needs to include a description of its use as a prescription drug. Ergocalciferol (D2) is formed from D3 by a step that occurs in the kidney. People with renal failure are unable to complete this conversion. Hence, the administration of converted D3, i.e., ergocalciferol is essential to health for people with this illness. 50.47.80.182 (talk) 06:06, 17 June 2011 (UTC)Reply

This is not quite right - D3 is converted to calcidiol by the liver and the kidney converts calcidiol into calcitriol. See Vitamin D. Seems that calcidiol and calcitriol have both D2 and D3 forms. eug (talk) 16:59, 28 July 2011 (UTC)Reply

D3 is native to animals, including humans. D2 is found in fungus, is an FDA approved drug, and is toxic in high doses to humans. The only reason to use D2 instead of D3 is to enhance drug company profits.

The American Journal of Clinical Nutrition published an article entitled "The case against ergocalciferol (vitamin D2) as a vitamin supplement" which contains very cogent comparison data in their Oct 2006 issue (see: http://ajcn.nutrition.org/content/84/4/694.full). — Preceding unsigned comment added by 108.33.100.226 (talk) 20:53, 7 February 2013 (UTC)Reply

D3 in plants? Yep

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While there is no doubt thar fungi and yeasts use ergosterol for structure and thus make D2 when exposed to UV, yet at the same time it is also true that a few plants make 7-dehydrocholesterol, perhaps as a dedicated light sensor, and thus make D3 with the aid of UV-- just to show nature is complicated [1].

The following chapter link probably can be got to, by googling "vitamin d3 from plants", as it has internal brackets in it that keep it from being used directly:

http://www.dtu.dk/upload/fødevareinstituttet/food.dtu.dk/publikationer/2012/phd-thesis-rie_japelt[1].pdf

Bottom line: some soreheads need to work this out in their worldviews. Sorry! SBHarris 20:50, 11 February 2013 (UTC)Reply

Concentration incomplete

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The Lichen section is sound but the Fungus and Plantae sections indicate masses of components instead of concentration levels. Perhaps the source mentions it or they assume it is per milligramme, per gramme or per 100 gramme but it should be indicated or there is no value in the quoted numbers.

Idyllic press (talk) 05:25, 18 March 2015 (UTC)Reply

typos

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Research concerning efficacy of vitamin D2 and D3 - 1,25-DIhydroxyvitamin D References - 4 is missing spaces; over should not be capitalized but Photochemistry & Photobiology should be. 9 - missing space. 13 - Journal, Clinical, & Nutrition should be capitalized. 69.72.92.100 (talk) 22:03, 21 December 2015 (UTC)Reply

You can fix it. Create an account, read this first, then I or others will check you. --Zefr (talk) 22:16, 21 December 2015 (UTC)Reply
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Big dose Vitamin D2 is very harmful for human health

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https://medicalxpress.com/news/2014-01-vitamin-d2-poor-choice-athletes.html "Taking vitamin D2 supplements decreased levels of vitamin D3 in the body and resulted in higher muscle damage after intense weight lifting.

During the double-blind study, one group of athletes consumed 3,800 international units (IU) a day of a plant-based vitamin D2. The other group of athletes took a placebo".

ee1518 (talk) 11:06, 21 January 2018 (UTC)Reply

See reply at Talk:Vitamin D. Alexbrn (talk) 11:53, 21 January 2018 (UTC)Reply