Talk:Genetics of Down syndrome

Meiosis 1 or 2?

There is something I don't understand, how would you, for instance, distinguish between a Down syndrome caused at the stage 1 of meiosis and the same at stage 2 of meiosis ? Thanks. XApple (talk) 14:23, 26 November 2007 (UTC)

Error in 'Possible Gametes from Translocation' Diagram?

How can a gamete contain both a 14/21 translocation and chromomsome 14 at the same time? Also, how can a gamete contain C21 on its own? —Preceding unsigned comment added by 78.16.154.143 (talk) 19:43, 28 November 2009 (UTC)

External links modified

Hello fellow Wikipedians,

I have just modified 5 external links on Genetics of Down syndrome. Please take a moment to review my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit this simple FaQ for additional information. I made the following changes:

• Added archive https://web.archive.org/web/20060707183834/http://www.iscn1995.org/ to http://www.iscn1995.org/
• Added archive https://web.archive.org/web/20060517062949/http://www.screening.nhs.uk:80/downs/home.htm to http://www.screening.nhs.uk/downs/home.htm
• Corrected formatting/usage for http://www.nichd.nih.gov/publications/pubs/downsyndrome/down.htm#TheOccurrence
• Corrected formatting/usage for http://www.nichd.nih.gov/publications/pubs/downsyndrome/down.htm#TheOccurrence
• Corrected formatting/usage for http://www.nichd.nih.gov/publications/pubs/downsyndrome/down.htm#TheOccurrence

When you have finished reviewing my changes, you may follow the instructions on the template below to fix any issues with the URLs.

This message was posted before February 2018. After February 2018, "External links modified" talk page sections are no longer generated or monitored by InternetArchiveBot. No special action is required regarding these talk page notices, other than regular verification using the archive tool instructions below. Editors have permission to delete these "External links modified" talk page sections if they want to de-clutter talk pages, but see the RfC before doing mass systematic removals. This message is updated dynamically through the template {{source check}} (last update: 5 June 2024).

• If you have discovered URLs which were erroneously considered dead by the bot, you can report them with this tool.
• If you found an error with any archives or the URLs themselves, you can fix them with this tool.

Cheers.—InternetArchiveBot (Report bug) 06:09, 9 January 2017 (UTC)

Moved to talk

I moved this addition to the talkpage:

It is theoretically possible that normal mothers of children with Down Syndrome may be chromosomal mosaics and that the abnormal chromosomal cells are in the ovarian tissue. The ova produced by such individuals contain trisomic cells and result in trisomic offspring. This type of mosaicism would not be detectable in cytological studies of the usual tissues. [http://%5Barchiveorg%20epidemiologyofmo00lili%20width=560%20height=384%20frameborder=0%20webkitallowfullscreen=true%20mozallowfullscreen=true%5D Epidemiology of mongolism]

The wording is off ("normal" mothers?). The link does not work. Polygnotus (talk) 01:25, 25 June 2024 (UTC)

Ah, I think the link should be https://archive.org/details/epidemiologyofmo00lili but that is a book from 1969 and not a reliable source. Polygnotus (talk) 01:29, 25 June 2024 (UTC)

@2601:680:C503:1A70:9938:5AE1:B0ED:E66C: We can't use a book that old (55 years...) for a medical claim. We have to follow WP:MEDRS. Better newer sources exist. Polygnotus (talk) 01:55, 25 June 2024 (UTC)