Talk:Genetics of post-traumatic stress disorder

This article was the subject of a Wiki Education Foundation-supported course assignment, between 19 January 2022 and 17 May 2022. Further details are available on the course page. Student editor(s): Neurobsessed (article contribs).

Study suggesting areas for more research Re susceptibility linkages

"Huge Study Explores Genetics of PTSD in More than 165,000 US Veterans", Paul Sisson, San Diego Union-Tribune

Recently published in the journal Nature Science by collaborating investigators at the University of California, San Diego and Yale University, the study is the first PTSD analysis to draw upon genetic information collected by the Million Veteran Program. Created by the U.S. Department of Veterans Affairs, the voluntary initiative seeks to create a medical database large enough that researchers can see patterns of genetic variation capable of providing indispensable road maps for the future treatment of many diseases.

Though the program does not yet have its full sampling of 1 million records available, there is already enough data in place to allow the research team to study more than 165,000 veterans. Using sophisticated computer modeling techniques, they were able to compare the genomes of those who experienced a key symptom of post-traumatic stress to those who did not. ... ... ...

A complex microbiological interplay decides which genes actually get expressed, and that dance is also affected by environmental factors. So, simply having a genetic difference itself is, researchers say, not likely to in-and-of-itself make a person more susceptible to PTSD. Epigenetics, the study of which genes within a person's DNA actually get expressed and how that translation occurs, are necessary to truly understand how genetic differences may influence real people. In terms of those medium spiny neurons, Stein said, the association study provides hints that could provide the starting point for deeper epigenetic studies that could determine how, and in which specific circumstances, genetic code differences deliver heightened PTSD susceptibility.

--Hodgdon's secret garden (talk) 20:01, 6 August 2019 (UTC)

PTSD genetics in diverse populations

By editing this article, I hope to contribute a further understanding of differences in genetic relationships with PTSD among a more diverse population, studying how these relationships exist and change across different racial groups or gender. Overall, this article is a great starting point with a long list of reliable sources and loads of information, and I hope that my future contributions help to create a more well-rounded article based off of the original author's hard work. Agreeves (talk) 16:22, 27 May 2023 (UTC)

Wiki Education assignment: Psychology Capstone

This article was the subject of a Wiki Education Foundation-supported course assignment, between 8 May 2023 and 11 August 2023. Further details are available on the course page. Student editor(s): Agreeves (article contribs). Peer reviewers: Aebner01, Cosmic Hypernova, Williabd, Mewallac, Sbradbeno98.

— Assignment last updated by Rahneli (talk) 20:02, 4 June 2023 (UTC)