Talk:Glycerol-3-phosphate dehydrogenase
Latest comment: 6 years ago by Linuxo in topic Duplicate page?
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EC-numbers
editIt is logical that the NAD-dependent is a different enzyme than the FAD-dependent one. So obviously, some databases are not that correct. --Yikrazuul (talk) 17:46, 29 May 2010 (UTC)
- I agree that a quinol-dependent enzyme is a different from a NAD-dependent one. However you have not provided a source that states that GPD1 is quinol dependent while GPD2 is NAD dependent. Are Brenda, OMIM, and UniProt that have all classified GPD1 as a 1.1.1.8 enzyme all wrong? Boghog (talk) 00:06, 30 May 2010 (UTC)
reaction mechanism
editThe GPD2 reaction mechanism seems to be out of order, or at least not rigorously accurate. It shows FAD being 'reduced' by 2 protons yet remaining electrically neutral, before the hydride ion even leaves the G3P. And then the hydride, which doesn't appear in the mechanism, magically becomes a free proton.
Duplicate page?
editI've found this page: https://en.wikipedia.org/wiki/Glycerol-3-phosphate_dehydrogenase_(quinone) and I think it describes (with a lot fewer details) exactly the same enzyme. Shouldn't that page there be deleted? Linuxo (talk) 09:36, 8 May 2018 (UTC)