Talk:Heterochromatin

Latest comment: 6 years ago by 98.194.39.86 in topic Heterochromatin - aka, We're not sure.

Untitled

edit

The second section is pretty unprofessional. Lazily Talks about the diagram being incorrect instead of simply fixing it. --Loftuale (talk) 06:13, 13 April 2017 (UTC)Reply

name

edit

The second section is pretty poorly done. The grammar is weird and it talks about the diagram being bad within the article.

What was the reasoning behind naming it heterochromatin? Is it correct that histone modifications like methylation, and acetylation cause the compacting of DNA? There seems to be a trend in literature concerning epigentics where increased transcription is linked to these modifications. —The preceding unsigned comment was added by 209.132.119.254 (talkcontribs) 20:20, 7 July 2005.

The folding of DNA is a complex mechanism regulated by several proteins in addition to methylation, and acetylation, proteins (other than histons) are involved as well. The full process isn't understood yet. One can imagine that some genes or several next to one another need to be activated upon some intracellular signals. some of these proteins may play a role in that. see also [1] —The preceding unsigned comment was added by Picobyte (talkcontribs) 11:02, 20 March 2006.

In general, acetylation of histones is associated with chromatin that contains genes that are actively being expressed; this acetylation can come from enzymes associated with transcription. Methylated histones are generally associated with chromatin that contains genes that are inactive or "silenced". —The preceding unsigned comment was added by 70.246.134.197 (talkcontribs) 01:55, 1 November 2005.

The above answer is not quite right. Methylated histones are NOT generally associated with chromatin condensation leading to genes that are inactive or "silenced". The effect is specific to the other histone modifications in the vicinity. Please see Histone methylation. Shyam (talk) 03:51, 8 December 2013 (UTC)Reply

Does the link ("Research news in heterochromatin") seem empty? Perhaps it should be deleted? Phycophile 15:16, 30 May 2007 (UTC)PhycophileReply

Heterochromatin - aka, We're not sure.

edit

Just say it in a few simple words: We don't yet understand how this section of the human genome works. It's OK to admit you don't know anything. Because after (trying) to read this article, that what I have learned. This part of the human genome wasn't mapped because doctors and / or scientists don't yet understand how it works or what it does. Just say that next time. Everyone can understand the statement "we don't know". 98.194.39.86 (talk) 13:07, 30 October 2018 (UTC)Reply