Why do hydroxamic acids act as HDAC inhibitors

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In HDAC inhibitor it says "[They] act exclusively on Class I and Class II HDACs by binding to the zinc-containing catalytic domain of the HDACs" Rod57 (talk) 22:14, 29 March 2011 (UTC)Reply

Presumably they'll also inhibit most/many other enzymes that have zinc or other metals in their catalytic domain. Rod57 (talk) 22:14, 29 March 2011 (UTC)Reply