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I think we have the wrong structure here, and the hydroxy bupropion metabolite that is made in the greatest quantities and has the greatest effects is actually hydroxylated on the ketone carbon due to a cyclization rather than remaining on the t-butyl group, and therefore has stereoisomers. The bupropion article seems to agree with this. If the cyclized versions are the form of the drug that exists in the human body, it makes more sense to have the article focus on those, especially given the role stereochemistry has on effects. 71.182.200.183 (talk) 22:46, 10 June 2020 (UTC)Reply