Talk:Hypopituitarism/GA2

GA Review

First off, thanks to all the contributors for working on this article to get it to review stage. Here are a few points I've noticed about the article, mostly to do with prose and mostly minor. I'll put it on hold until these are addressed, shouldn't take long, and then I'll pass the article.

Up until end of "Causes" section

1. "The most common problem is insufficiency of LH and/or FSH leading to sex hormone abnormalities." — Perhaps use the full terms for LH and FSH here, introduce the abbreviations, instead of doing it in the section afterwards called "Anterior pituitary". The same applies to growth hormone (GH).

    Done JFW | T@lk 19:12, 18 August 2008 (UTC)

2. Bracket-explain the terms "pituitary apoplexy" and "lymphocytic hypophysitis" under signs and symptoms opening paragraph.

    Done JFW | T@lk 19:12, 18 August 2008 (UTC)

3. "Both sexes may experience a decrease in libido, loss of sexual function, and.." — Why is libido explained through commas instead of brackets? Could probably do with being consistent throughout the article.

    Done Clarified; they are different concepts. JFW | T@lk 19:12, 18 August 2008 (UTC)

4. Link jargon such as "oxytocin", "testosterone", "exogenous", "osmolarity", "hypoplasia"

    Done JFW | T@lk 19:12, 18 August 2008 (UTC)

5. The last sentence under "Basal tests" could probably be combined with the previous two sentence paragraph. One sentence paragraphs are discouraged.

    Done JFW | T@lk 19:12, 18 August 2008 (UTC)

6. The last review had issues with the causes table being the only thing in the Causes section. Seeing as it's now made up from several sources, I have no issue with this.

    Done At least with a table it is easier to show your surgical sieve. JFW | T@lk 19:12, 18 August 2008 (UTC)

Content issues

1. A quick search of PubMed shows several things which may or may not be covered in the article.

• Metyrapone testing? (PMID 18664544)

• Not sure if the Dorin review mentions this. I will investigate. JFW | T@lk 19:12, 18 August 2008 (UTC)
• Dorin et al mention this. I have added mention of the metyrapone stimulation test. JFW | T@lk 19:25, 18 August 2008 (UTC)

• I'm not familiar with the WP:MED guidelines for referencing definitions such as "panhypopituitarism" but are there no available PubMed articles that can be found to cite the existence of such a condition? All I've seen is a Dorlands Medical Dictionary reference. However, seeing as I'm not sure and I doubt it's that bigger deal, it'd be unwise to fail the article on this basis. There is a brief mention of the condition here, although I haven't checked the content: PMID 18558595.

• The difference is academic. Hypopituitarism is usually associated with deficiency of 3 or more hormones, so it is more a label than actually having any influence on management. 19:12, 18 August 2008 (UTC)

Great work on the article folks! —Cyclonenim^T@lk? 10:42, 18 August 2008 (UTC)