Talk:Indometacin

Untitled

In accordance with Wikipedia:WikiProject_Drugs naming policy, I propose we move this page to the INN indometacin. If you have any concern with this proposal, please discuss it on this page. Matt 17:48, 23 Dec 2004 (UTC)

As per policy and in keeping with similar moves for all drugs with INN/USAN/BAN differing names, the INN is the official worldwide name that should be used (see also existing interwiki links showing names on other language wikipedia). So moved from indomethacin to indometacin. David Ruben ^Talk 01:44, 18 July 2006 (UTC)

References

A lot of the references (apart of course from Hart et al) are not quoted at all and seem irrelevant to the article content. May I remove them? JFW | T@lk 12:24, 5 Jun 2005 (UTC)

Someone really needs to update the referenced list of conditions Indomethacin is a treatment for - it is disorganised, scrappy and in some cases dubious. Tigeh (talk) 00:52, 11 June 2014 (UTC)

Cluster Headaches

It might be worth mentioning that Indometacin is used as a drug to perform differential diagnosis (DDX) between cluster headaches, which it doesn't work on, and chronic paroxysmal headache, which almost universally responds to a course of indomethacin.Tigeh (talk) 00:52, 11 June 2014 (UTC)

FDA and Increased Risk of Heart Disease

According to http://www.nytimes.com/2015/07/10/us/fda-is-set-to-toughen-nonaspirin-warnings.html?_r=0 the FDA is stiffening labeling requirements for NSAID drugs to better reflect the link to heart disease. The article mentions only ibuprofen by name, but evidently the issue and new labeling applies to all NSAID drugs. As indometacin is in that class, it would seem to apply and warrant mention here, but I am loathe to add that without explicit confirmation. — Preceding unsigned comment added by 184.70.8.54 (talk) 14:21, 10 July 2015 (UTC)

Latin names vs. Common names

Although "ulcus ventriculi and/or duodeni" and "Morbus Parkinson" may be clear to the medical community, it would serve the lay public better to call these conditions by their common names - "Peptic or Stomach Ulcers" and "Parkinson's Disease". 208.186.183.162 20:29, 19 June 2006 (UTC)

Title

I've more commonly seen this referred to as "Indomethacin". I submit that the title should be changed to Indomethacin primarily, Indometacin secondarily.Dryphi (talk) 05:09, 19 March 2012 (UTC)

I disagree - while that is it's trade name, it isn't the INN and according to wikipedia policy the INN should be used. Even though everyone thinks the INN has the 'h' in it anyway. Tigeh (talk) 00:52, 11 June 2014 (UTC)

I think the "h" belongs in the article name, per WP:COMMONNAME.

Although official, scientific, birth, original, or trademarked names are often used for article titles, the term or name most typically used in reliable sources is generally preferred.

and

In determining which of several alternative names is most frequently used, it is useful to observe the usage of major international organizations, major English-language media outlets, quality encyclopedias, geographic name servers, major scientific bodies, and notable scientific journals. A search engine may help to collect this data; when using a search engine, restrict the results to pages written in English, and exclude the word "Wikipedia". When using Google, generally a search of Google Books and News Archive should be defaulted to before a web search, as they concentrate reliable sources (exclude works from Books, LLC when searching Google Books). Search engine results are subject to certain biases and technical limitations; for detailed advice on the use of search engines and the interpretation of their results, see Wikipedia:Search engine test.

Doing the above described google search finds preference for "indomethacin -wikipedia" favored by 3:1 over "indometacin -wikipedia". This may be the result of a WP:ENGVAR, it's clear that US organizations use the "th" spelling, while British organizations use the "t" version. Tarl.Neustaedter (talk) 19:19, 11 May 2015 (UTC)

I agree but note that a defining factor is the pronunciation; the US is commonly 'th' but the British is "t".

I'm unsure what Tigeh meant by saying that Indomethacin is a trade name; I take it to be the same as a brand name in that it is a name used by a manufacturer who has proprietary rights over it.

In that case, I disagree with Tigeh, because "Indomet(h)acin" is assuredly not a trade name but a commonly used name for the drug in any oral form, generic or otherwise. Contrast that with Indocin (for example) which is certainly a brand name for the drug.2602:30A:2C4A:1CB0:2C4E:2BC2:CCD3:83A9 (talk) 21:34, 31 October 2016 (UTC)

Addition to Adverse effects

A sentence was just added to Indometacin#Adverse effects: In women who are pregnant, it has been shown that use of this medication can have an effect of the fetal (Baby's) heart possibly resulting in fetal death.

I'm not sure that is needed. The article referenced presents three case studies where a fetus was damaged by premature ductus arteriosus closure. But managing patent ductus arteriosus is one of the clinical uses specified in the earlier paragaph Indometacin#Medical uses. Any other opinions on whether the change is superfluous? Tarl N. (discuss) 00:38, 11 July 2016 (UTC)

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Ranitidine?

The article advocates ranitidine to counter adverse g.i. effects. Ranitidine is no longer available. I'm not sufficiently up on current therapy to be comfortable making a change. Cimetidine? Famotidine? Toyokuni3 (talk) 00:17, 20 June 2024 (UTC)