Talk:Iron deficiency

Spinach is not as good as people think

An interesting abstract on pubmed indicates that: 1. Spinach is a poor source of dietary iron 2. Ascorbic Acid (vitamin C) doubles the iron absorbed from spinach.

Posted this hoping there's someone will find a good place to work this into the article. -- Matthew 1130 11:39, 14 April 2007 (UTC)

Iron deficincy anaemia

There is one page on "Iron deficiency anaemia" and one page on "iron deficiency (medicine)". They are closely related topics and perhaps they should be merged. Perhaps, a decision on a merge could by made by a consensus opinion soon and in the early stages of this subjects "medicine collaboration of the week", in order to prevent confusion at a later stage.

I would vote for the pages to be merged. Snowman 19:32, 30 January 2007 (UTC)

I agree --Emevas 21:03, 30 January 2007 (UTC)

Agreed Badgettrg

Disagreed. Different topics, big articles. `'mikka 20:56, 8 February 2007 (UTC)

References

i also strongly dissagree...ahsan masood

Changed table

I replaced table under "Good Natural Sources of Iron (Foods)" since previous was vegy oriented and didn't include any heme iron group (fish-meat). Its not perfect, dosages aren't very specific, but I think it has enough variety.

milk

Milk seems to block the absoption of iron contained in iron-fortified cereals. Does anyone have a source for this? Tkuvho (talk) 04:54, 7 October 2010 (UTC)

Addition in the article

I made changes in the article by further adding information on what Iron Deficiency Anemia is and its causes, in the second paragraph.

SR95 (talk) 02:22, 12 August 2014 (UTC)

Serving size

Why is the serving size 100g for all the meats and differing amount for vegetables? It seems heavily skewed towards soya.

213.235.58.157 (talk) 07:10, 27 February 2015 (UTC)

Tendinopathy an effect of iron deficiency?

Moved here from main article the claim that tendinopathy is caused by iron deficiency.

The study cited for this claim says only that fluoroquinolones (FQ) cause tendinopathies, and suggests fluoroquinolone-related iron chelation, not iron deficiency per se, causes tendinopathies:

"Badal S1, Her YF1, Maher LJ 3rd2. "J Biol Chem. 2015 Jul 23. pii: jbc.M115.671222. [Epub ahead of print] "*Non-antibiotic effects of fluoroquinolones in mammalian cells.*

"*Abstract*

"Fluoroquinolones (FQ) are powerful broad-spectrum antibiotics whose side effects include renal damage and, strangely, tendinopathies. ... "

PMID 26205818 http://www.ncbi.nlm.nih.gov/pubmed/26205818

The free full text suggests a role of iron chelation at page 6:

These results suggest, for the first time, that FQ treatment can cause unanticipated epigenetic effects. Moreover, we suggest that the well-established linkage between FQ treatment and tendinopathy reflects impairment of collagen maturation by FQ. We suggest that it is the inhibition of collagen 4 prolylhydroxylases by FQ- mediated iron chelation, and repression of collagen P4H1 and LH1transcription that underlies the peculiar tendinopathy side effects of FQ antibiotics. ...

The study's conclusion:

Thus, we propose that iron chelation by FQ antibiotics explains tendinopathy and nephrotoxicity in part through inhibition of iron-dependent dioxygenase enzymes.

http://www.jbc.org/content/early/2015/07/23/jbc.M115.671222.full.pdf

iron amount in clam

The table has clam at #1 with 28 mg of iron per 100 g. However, http://nutritiondata.self.com/facts/finfish-and-shellfish-products/4184/2 has "Mollusks, clam, mixed species, canned, liquid" entry with only 0.3 mg per 100 g. That is roughly a percent of what this article claims. Though the list also has "mussel" at #8, and isn't mussel also a sort of a clam? 212.50.203.198 (talk) 07:15, 12 November 2015 (UTC)

So, that was the one I got with Google search. Now I found entry "Mollusks, clam, mixed species, canned, drained solids" which has 44.7 mg per 100g. And that is over 1.5 more than given in this wiki article... 212.50.203.198 (talk) 07:25, 12 November 2015 (UTC)

Sorry, that wasn't per 100 g. The default portion size was bigger, and the amount per 100 g is indeed 28 mg. 212.50.203.198 (talk) 17:21, 12 November 2015 (UTC)

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Things that reduce iron absorption.

It has been suggested by different sources that green tea, black tea and coffee reduce the amount of iron absorption by the body. — Preceding unsigned comment added by Thecuriousmind (talk • contribs) 10:40, 25 November 2018 (UTC)

The way requirements for women are documented in the source material is terrible.

<rant>I was just researching this for non-Wikipedia reasons and all of the detailed medical discussions make it totally clear that the two adult RDAs are basically 8 mg/day for non-menstruating adults and 18 mg/day for menstruating adults. So why is it always written as a function of age rather than menstruation status? It all traces back to the USDA which says "women 18–50" as if every woman experiences menopause at age 50, menstrual suppression or other causes of amenorrhea aren't a thing, hysterectomies never happen, transwomen don't exist, etc., etc.

Likewise, the RDAs for teens are written as if all girls start menstruating on their 14th birthdays, which hasn't even been true on average for a couple of centuries; see Menarche § Changes in time of average age.

All the sources I found parrot the age-based guidelines and then add a lot of exceptions, rather than just using a simpler formulation in the first place.

Yeah, a little extra doesn't hurt, but iron overload is a thing and the therapeutic index for dietary iron is not that wide; the normal upper intake limit for adults is 45 mg/day (and there exist people who are more sensitive), so factors of 2.25 shouldn't be thrown around willy-nilly. Phrasing it in terms of menstruation would also make clear that individuals might want to adjust based on how much they are menstruating.

I wish to hell WP could just document it in terms of menstruation rather than age, but I can't find a sufficiently authoritative WP:RS which explicitly states the glaringly obvious, so it would be WP:OR. ☹️

</rant>, but if anyone can track down a good source, please please add it. Thank you. 97.102.205.224 (talk) 18:16, 29 October 2024 (UTC)

Update The WHO seems to do things more sensibly, e.g. Guideline: Daily Iron Supplementation in Adult Women and Adolescent Girls, Vitamin and mineral requirements in human nutrition, 2nd edition. The latter uses an age-based table during childhood and puberty, but clearly marks its menarche assumptions, and divides adult women into pre- and postmenopausal rather than making any age assumptions. 97.102.205.224 (talk) 12:37, 31 October 2024 (UTC)