Talk:Kynurenine

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Possible drug target for cancer treatment

[1] has developed an enzyme to degrade K to allow cancer immunotherapies to work better. See if they get an IND for clinical trials. - Rod57 (talk) 18:11, 13 September 2018 (UTC)

Like recent specialized publications on topics one doesnt understand? Try these on

Here are the rules: No Spamming (WP:COI) Yes to WP:SECONDARY Yes to WP:TERTIARY No to news WP:NOTNEWS

For 2024, here are the publications.

T1 - Utilizing transcriptomics and metabolomics to unravel key genes and metabolites of maize seedlings in response to drought stress T1 - ARID5A stabilizes Indoleamine 2,3-dioxygenase expression and enhances CAR T cell exhaustion in colorectal cancer T1 - Integration of lipidomics and metabolomics reveals plasma and urinary profiles associated with pediatric Mycoplasma pneumoniae infections and its severity T1 - Mating-induced increase of kynurenine in Drosophila ovary enhances starvation resistance of progeny T1 - Investigation of tryptophan to kynurenine degradation in response to interferon-γ in melanoma cell lines T1 - Zinc Ameliorates Cadmium-Induced Immunotoxicity by Modulating Splenic Immunosuppressive Indoleamine 2,3-Dioxygenase Activity, Hematological Indices, and CD4+ T Cells via Inhibition of Cadmium Uptake in Male T1 - Comparative secretome metabolic dysregulation by six engineered dietary nanoparticles (EDNs) on the simulated gut microbiota T1 - Effect of different stress conditions on the formation of amino acid derivatives by Brewer's and Baker's yeast during fermentation T1 - Microbial biomarkers of risk for infection after liver transplant T1 - Construction method for intestinal microorganism-related metabolite mass spectrometry database and use thereof T1 - Effects of dietary rumen-protected choline supplementation to periparturient dairy cattle on inflammation and metabolism in mammary and liver tissue during an intramammary lipopolysaccharide challenge T1 - Silencing of aryl hydrocarbon receptor repressor restrains Th17 cell immunity in autoimmune hepatitis T1 - Verification studies of tryptophan and kynurenine determination using HPLC and evaluation of the kynurenine pathway and neopterin levels in human colostrum samples T1 - Role of metabolomic profile as a potential marker to discriminate membranous nephropathy from IgA nephropathy T1 - Aflatoxin B1-induced redox imbalance in the hippocampus and cerebral cortex of male Wistar rats is accompanied by altered cholinergic, indoleaminergic, and purinergic pathways: Abatement by dietary rutin T1 - Oligonucleotides targeting indoleamine 2,3-dioxygenase and uses for treating cancer and neutonal disease T1 - Oligonucleotides targeting indoleamine 2,3-dioxygenase for treating cancer and neuronal disease T1 - Comparison of the impact of UV-light emitting diode and UV lamp at pilot-plant scale level on quality parameters and consumer perception of fresh chicken meat T1 - Method of producing mixture of biologically active substances: biogenic amines histamine, tryptamine, tyramine, kynurenine, as well as kynurenine derivative - kynurenic acid T1 - Protein therapeutics for treatment of senescent cells T1 - T cell epitopes associated with type 1 diabetes T1 - Detection of metabolites using a microfluidic-based CE-MS system, and diagnostic applications T1 - Co-exposure to sodium hypochlorite and cadmium induced locomotor behavior disorder by influencing neurotransmitter secretion and cardiac function in larval zebrafish T1 - Imidacloprid affects the visual behavior of adult zebrafish (Danio rerio) by mediating the expression of opsin and phototransduction genes and altering the metabolism of neurotransmitters T1 - Gas chromatography-mass spectrometry-based quantitative method using tert-butyldimethylsilyl derivatization for plasma levels of free amino acids and related metabolites in Japanese Black cattle T1 - The contributions of neonatal inhalation of copper to air pollution-induced neurodevelopmental outcomes in mice T1 - Efficient production of an antitumor precursor actinocin and other medicinal molecules from kynurenine pathway in Escherichia coli T1 - Fatty acid modification of casein bioactive peptides nano-assemblies, synthesis, characterization and anticarcinogenic effect T1 - Kynurenic acid: translational perspectives of a therapeutically targetable gliotransmitter T1 - MARS: A Multipurpose Software for Untargeted LC-MS-Based Metabolomics and Exposomics T1 - Neuroprotective mechanisms of defatted walnut powder against scopolamine-induced Alzheimer′s disease in mice revealed through metabolomics and proteomics analyses T1 - Impact of using whole chestnut flour as a substitute for cake flour on digestion, functional and storage properties of chiffon cake: A potential application study T1 - Immunotolerance inducing composition for treating gestational hypertension T1 - Comparative metabolomic analysis and antigenicity comparison of cow milk and enzymatically treated cow milk T1 - Use of plasma molecular marker kynurenine in detection of early heart failure T1 - Guanosine diphosphate-mannose suppresses homologous recombination repair and potentiates antitumor immunity in triple-negative breast cancer T1 - Method for characterizing a vaginal microbial community and device, computer program and computer readable medium for executing said method T1 - Methods for determining impairments in neuro-metabolism in a subject in need thereof & means useful in the treatment thereof T1 - Selective inhibition of indoleamine and tryptophan 2,3-dioxygenases: Comparative study on kynurenine pathway in cell lines via LC-MS/MS-based targeted metabolomics T1 - Disposable Molecularly Imprinted Polymer-Modified Screen-Printed Electrodes for Rapid Electrochemical Detection of l-Kynurenine in Human Urine T1 - Distinct Metabolic Profiles of Ocular Hypertensives in Response to Hypoxia T1 - Patients with Neurodegenerative Proteinopathies Exhibit Altered Tryptophan Metabolism in the Serum and Cerebrospinal Fluid T1 - A comparative study of plasma and dried blood spot metabolomics and its application to diabetes mellitus

Want more?, 400+ in 2023.  5000+ total.--Smokefoot (talk) 19:52, 23 March 2024 (UTC)