Talk:Lewis antigen system

Latest comment: 16 years ago by Taucetiman in topic Untitled

Untitled

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There are also HLA antigens that also can be absorbed onto RBCs Taucetiman (talk) 21:08, 2 October 2008 (UTC)Reply

Biosynthesis of Lewis antigens

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The section 'Lewis Related Genes' contains a lot of mistakes!

  • Corrections that can be made:
    1. There are 6 oligosaccharide precursors.
    2. The Se-enzyme can act only on type 1 precursor before any modification of the Le-enzyme.
    3. The Le-enzyme can act on various substrate: type 1 precursor(producing Le(a)) , H type 1 antigen (producing Le(b)), A type 1 (producing ALe(b)) and B type 2 (producing BLe(b))...
  • I didn't modify the text because it needs a complete reformulation.
  • here are some references:

http://www.sciencedirect.com/science/article/pii/S0300908401013219

http://jhc.sagepub.com/content/46/1/69.full