Talk:Loss of heterozygosity
Latest comment: 7 years ago by Tedtoal in topic One more form of LOH not described
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Statement Needs Clarification
editThe statement in the introductory paragraph that "The majority of the genome within somatic cells of individuals are heterozygous" is confusing. Can someone please clarify?
- That statement is confusing. I've rewritten it to hopefully be more clear; see what you think. --Mark viking (talk) 18:52, 2 September 2013 (UTC)
History of LOH
editThe article could use at least a brief history. When was LOH first identified? None of the references at the end are older than ten years -- surely people knew of LOH before 2004? — Preceding unsigned comment added by 128.250.5.254 (talk) 02:14, 18 June 2014 (UTC)
One more form of LOH not described
editIn copy-neutral LOH, there is one other way it can happen: a second mutation hit (normally at a different location) in the remaining good allele. I believe most researchers would refer to this as LOH, wouldn't they? Tedtoal (talk) 21:19, 15 September 2017 (UTC)