Talk:N-Glycolylneuraminic acid

Latest comment: 5 years ago by Phantom in ca in topic New PNAS study (2019 July) reported in Guardian

New evidence

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New evidence: http://medicalxpress.com/news/2014-12-sugar-molecule-neu5gc-links-red.html Totinen (talk) 10:14, 3 January 2015 (UTC)Reply

More specifically: http://www.pnas.org/content/early/2014/12/25/1417508112.abstract Arda Xi(Talk) 16:27, 3 January 2015 (UTC)Reply

Amount of Neu5gC in horse meat? Can you find a reliable source?

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https://www.telegraph.co.uk/news/science/science-news/3346666/Mystery-of-the-meat-eaters-molecule.html 12:01AM BST 08 Jul 2008

Exact amount in horse meat is not mentioned in that article(?)

ee1518 (talk) 15:52, 6 October 2018 (UTC)Reply

New study (Sep 2018) shows there is no evidence that Neu5gc increases colon cancer risk

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162487/

Murphywmm (talk) 22:36, 13 July 2019 (UTC)Reply

New PNAS study (2019 July) reported in Guardian

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"In the study, published in PNAS, researchers genetically modified mice to be more like humans in their deficiency of a sialic acid sugar molecule called Neu5Gc. They found the atherosclerosis in these mice was nearly twice as severe as that in unmodified mice.

The study also looked specifically at the effect of eating red meat. When humans eat animal flesh which contains Neu5Gc molecules, “it’s like a Trojan horse”, said Varki. “It sneaks in and causes an inflammatory immune response.”

To mimic this effect, the researchers fed the genetically modified mice a high-fat diet which was rich in Neu5Gc. These mice suffered an increase in atherosclerosis 2.4 times that of unmodified mice fed the same diet."

From: https://www.theguardian.com/society/2019/jul/22/genetic-mutation-made-humans-susceptible-to-heart-attacks-study

Phantom in ca (talk) 20:24, 23 July 2019 (UTC)Reply