Talk:N-Glycolylneuraminic acid
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New evidence
editNew evidence: http://medicalxpress.com/news/2014-12-sugar-molecule-neu5gc-links-red.html Totinen (talk) 10:14, 3 January 2015 (UTC)
Amount of Neu5gC in horse meat? Can you find a reliable source?
edithttps://www.telegraph.co.uk/news/science/science-news/3346666/Mystery-of-the-meat-eaters-molecule.html 12:01AM BST 08 Jul 2008
Exact amount in horse meat is not mentioned in that article(?)
New study (Sep 2018) shows there is no evidence that Neu5gc increases colon cancer risk
editNew PNAS study (2019 July) reported in Guardian
edit"In the study, published in PNAS, researchers genetically modified mice to be more like humans in their deficiency of a sialic acid sugar molecule called Neu5Gc. They found the atherosclerosis in these mice was nearly twice as severe as that in unmodified mice.
The study also looked specifically at the effect of eating red meat. When humans eat animal flesh which contains Neu5Gc molecules, “it’s like a Trojan horse”, said Varki. “It sneaks in and causes an inflammatory immune response.”
To mimic this effect, the researchers fed the genetically modified mice a high-fat diet which was rich in Neu5Gc. These mice suffered an increase in atherosclerosis 2.4 times that of unmodified mice fed the same diet."