Talk:Oligosaccharide

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Health benefits?

This text (sources) says the exact opposite of what the article claims: oligosaccharides give soy its notorious reputation as a gas producer. Although these are present in all beans, soy is such a powerful "musical fruit" that the soy industry has identified "the flatulence factor" as a major obstacle that must be overcome for soy to achieve full consumer acceptance. Sounds like you shouldn't rely on oligosaccharides to help against Irritable Bowel Syndrome, as the article suggests. So who's right?--87.162.30.16 (talk) 16:41, 8 October 2008 (UTC)

Flatulence and irritable bowel syndrome are different things. IBS causes bloating, discomfort and general disruption that may in some cases also result in flatulence, but this is a side effect of any gas production rather than a symptom. It is quite possible that oligosaccharides may alleviate IBS symptoms (that is: pain, bloating etc.) while increasing flatulence. --Nessunome (talk) 18:53, 24 January 2014 (UTC)

Therapeutic effects

The entire 'therapeutic effects' section has NO references and makes some pretty specific claims (among them the existence of these uncited clinical studies.) Considering the article is already focused primarily on the structure and biochemistry of these molecules, perhaps this should be cut until someone is willing to write a referenced and less-salesy version of this section? Or perhaps just a few links to the controversy. Any objections to this being removed? Is this worth a separate article? --Glycoform (talk) 20:52, 3 May 2009 (UTC)

Please move it to the talk page until someone comes up with a decent reference/study to suggest some sort of validity to the data Ianmc (talk) 22:31, 5 May 2009 (UTC)

Done.

Original text from Therapeutic Effects ---Glycoform (talk) 22:59, 19 May 2009 (UTC)

Other benefits noted with FOS, GOS, or inulin supplementation include increased production of beneficial short-chain fatty acids such as butyrate, increased absorption of calcium and magnesium, and improved elimination of toxic compounds.

Because FOS, GOS, and inulin improve colon function and may influence the bacterial composition, one might expect these compounds would help relieve the symptoms of irritable bowel syndrome. However, a double-blind trial found no clear benefit with FOS supplementation (2 grams three times daily) in patients with this condition.

Experimental studies with FOS in animals suggest a possible benefit in lowering blood sugar levels in people with diabetes and in reducing elevated blood cholesterol and triglyceride levels.

In a double-blind trial of middle-aged men and women with elevated cholesterol and triglyceride levels, supplementation with inulin (10 grams per day for eight weeks) significantly reduced insulin concentrations, suggesting an improvement in blood-glucose control, and significantly lowered triglyceride levels.

In a preliminary trial, administration of FOS (8 grams per day for two weeks) significantly lowered fasting blood-sugar levels and serum total-cholesterol levels in patients with type 2 (non-insulin-dependent) diabetes.

However, in another trial, people with type 2 diabetes supplementing with FOS (15 grams per day) for 20 days found no effect on blood-glucose or lipid levels. Because of these conflicting results, more research is needed to determine the effect of FOS and inulin on diabetes and lipid levels.

Several double-blind trials have looked at the ability of FOS or inulin to lower blood cholesterol and triglyceride levels. These trials have shown that in people with elevated total cholesterol or triglyceride levels, including people with type 2 (adult onset) diabetes, FOS or inulin (in amounts ranging from 8 to 20 grams daily) produced significant reductions in triglyceride levels. However, the effect on cholesterol levels was inconsistent. In people with normal or low cholesterol or triglyceride levels, FOS or inulin produced little effect.

Adding Sections - Glycosylation, Functions, Role in Blood Types

Hello! I was hoping to add some information to this page to better explain the biochemical importance of Oligosaccharides. I wanted to include the following new sections to this article. (1) Role in Glycosylation - including the relevance, properties, and biochemical nature of N-linked Oligosaccharides and O-linked Oligosaccharides and its relevance to glycoproteins and glycolipids, . (2) Functions including (a) cell adhesion, and (b) cell recognition, both of which as they relate to glycoproteins and glycolipids. and then (3) an example under cell recognition that discusses glycolipids and their role in determining blood types. — Preceding unsigned comment added by Lizziechka (talk • contribs) 23:32, 27 October 2015 (UTC)

Wiki Education assignment: Virology 2022

This article was the subject of a Wiki Education Foundation-supported course assignment, between 23 August 2022 and 15 December 2022. Further details are available on the course page. Student editor(s): Hbl711, Feastann (article contribs). Peer reviewers: FireWhirls, Celebrations18!.

— Assignment last updated by FloeEdge (talk) 04:08, 20 October 2022 (UTC)