Talk:Palmitoylation
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Wiki Education Foundation-supported course assignment
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This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Peer reviewers: Sivart13.
Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 06:03, 17 January 2022 (UTC)
Expansion
editI'd like to see sections on the exact chemical reaction, perhaps the enzymes that enact palmitoylation, and also the biological role of palmitoylation (directing proteins to the membrane). I don't know much about palmitoylation, but if I have time I'll look stuff up and try to add it. --MPW 21:50, 17 October 2006 (UTC)
reversibility
editThe page has the text: "palmitoylation is usually reversible (because the bond between palmitic acid and protein is often a thioester bond)." However, there is no direct primary citation for this and the link to https://en.wikipedia.org/wiki/Palmitoyl_protein_thioesterase indicates that that enzyme acts during protein degradation, which would not mean that palmitoylation is "reversible" in the implied sense (which is that the protein can have the palmitoyl removed and continue to act, but with different subcellular localization due to the removal of the palmitoyl group). — Preceding unsigned comment added by 65.100.24.41 (talk) 06:42, 10 March 2017 (UTC)
Perhaps a better reference for the reversibility of palmitoylation in particular is here: http://www.sciencedirect.com/science/article/pii/S0005273611002148 — Preceding unsigned comment added by 65.100.24.41 (talk) 06:44, 10 March 2017 (UTC)