Talk:Paradoxical reaction
 | This article is rated Start-class on Wikipedia's content assessment scale. It is of interest to the following WikiProjects: | ||||||||||
| |||||||||||
This article needs work.
editIs this simply to become a listing of paradoxical reactions? If so, then nearly every drug could be listed since there is most likely some patient that has a paradoxical reaction to it. Or certain drugs which under non-ideal situations could act paradoxically (like anti-arrhythmic drugs which could paradoxically cause MIs). This article is important, however it may need to be rethought and reorganized. --98.70.56.46 (talk) 00:55, 31 October 2011 (UTC)
Genetics
editI'd like to see information about the role of genetics in paradoxical reactions included in this article. — C M B J 03:01, 9 August 2012 (UTC)
Needs More Recent Research
editThe resources at the bottom (most of them) are abysmally old. 23 and 24 year old research on the paradoxical reactions to anti-depressants? One source is from 1948, another from 1975, and still another from 1980. Medical research moves fast. Sources no older than 10 years would be much better on this topic - ideally, no older than five years, and there is plenty out there.
The constant citation of a few odd case reports to substantiate ADHD-specific paradoxical responses is not appropriate
editA few editors have added to the page relating to the supposed paradoxical effect of stimulants in ADHD. Most have based their edits on controlled research and preclinical studies demonstrating a lack of true ADHD-specific response with regards to behavioral effects at therapeutic doses. However, there is are a persistent string of edits citing a single case report which mentions, in passing, that the authors have observed paradoxical effects in ADHD patients relating to caffeine (without comparison to non-ADHD). No citation is provided, and this is not the main call to action of the article. Observed paradoxical reactions to anesthesia are.
Perhaps there is a paradoxical response specific to ADHD, even if the current research we have on amphetamine and methylphenidate suggest otherwise, but research to support this is non-existent, so anything more than acknowledgment of this belief shouldn't be included in the article. Oro Temp (talk) 03:19, 8 August 2024 (UTC)