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Chemical structure
editPersin was identified as (Z,Z)-1-(acetyloxy)-2-hydroxy-12,15-heneicosadien-4-one in 1995. A rough condensed structure is as follows: CH3C=OOCH2CHOHCH2C=OR, where R has two unconjugated double bonds (both double bonds are Z, or "trans"). Note also that the hydroxyl and the ketonyl carbonyl have an aldol relation (a beta-hydroxy ketone), typically created by an aldol condensation.
CAS
editThe CAS-link gives "No CAS Registry Number® matched your search."
91.156.5.58 (talk) 19:26, 1 December 2014 (UTC)
- The link goes to a Chemical Abstracts page that only verifies "common chemicals", and everything else gives the result you saw. -- Ed (Edgar181) 14:25, 2 December 2014 (UTC)
Other Foods Toxic to Pets
editRegarding the section of other foods toxic to pets, shouldn't this go in its own page? It has nothing to do with persin. Just my $0.02.
Naisenu 19:57, 31 August 2007 (UTC)
- Yeah, that's all covered elsewhere. I removed it. --Joelmills 02:44, 1 September 2007 (UTC)
The references need to be tracked back to the original source. Given the wild birds and my chickens love the avocados on my trees, when I found out they were considered highly poisonous to birds, I went looking for references. Eventually tracked it back, to the only study I could find. They injected(!) avocado directly into budgie (I think) birds. A number of them died. Hardly conclusive evidence that avocados are poisonous to birds. I have tracked down references, but don't have access to the journal, and it appears to not be online. These are the three ref's that need checking out:
https://www.ncbi.nlm.nih.gov/pubmed/2914792 https://www.ncbi.nlm.nih.gov/pubmed/1577644 https://www.ncbi.nlm.nih.gov/pubmed/1639676
Why are humans different?
editDoes anyone know why humans don't react like other mammals? How about chimps? If there are any references to reliable sources explaining why, this would be a nice addition to the page. Guy Macon (talk) 17:07, 15 September 2011 (UTC)
harmful for humans
editThe research paper analyszing the effect on mammary cells and heart cells speaks even about "mammals", i'm not sure how it can be concluded it is safe for humans? 100mg/kg are given for serious necrosis in mice mammary gland tissue (and also the myocardial tissue). Shaddim (talk) 16:10, 20 October 2016 (UTC) there seems to be an paper between 1997 and 2006 which concluded that Persin is harmless/not very harmfull to human mammary gland cells...but couldn't track it down. would be great if someone could add it. Shaddim (talk) 13:30, 21 October 2016 (UTC)