Talk:Polyhexanide

Latest comment: 2 years ago by 82.69.3.220 in topic Polyhexanide In eye drops.

Merger proposal

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I propose to merge Polyaminopropyl biguanide into Polyhexanide. It seems that polyaminopropyl biguanide (PAPB) is just a synonym for polyhexamenthylene biguanide (PHMB) or polyhexanide. EU regulation statements on PHMB (see 2015 report and 2016 report) list PAPB as a synonym for PHMB. Polyaminopropyl biguanide is the approved INCI name for the PHMB molecule. The SpecialChem database uses PHMB as an abbreviation for Polyaminopropyl biguanide, which is listed under the same CAS number as PHMB (32289-58-0). For this reasons, it is probably better to merge both articles. Please, let me know if you have any objections. Luis Bentolila (talk) 00:09, 8 February 2020 (UTC)Reply

Oppose on the grounds that these are related but different compounds (different CAS numbers, different structures); while uses are similar I think that it would be better to keep them separate, but linked (as is already done via a see also on both pages). Klbrain (talk) 20:16, 6 September 2020 (UTC)Reply

Polyhexanide In eye drops.

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I have been given sodium chloride 5% eye drops and PHMB is a preservative within this solution. While using this 7 times a day and night, I felt nauseous and unbalanced, especially when exposed to bright sunlight where contrast was strong. I cannot find a reference to these side effects anywhere. When I stop using the eye drops these symptoms abate. I have to conclude PHMB has some unpleasant effect here. 82.69.3.220 (talk) 11:05, 7 March 2022 (UTC)Reply