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Reproductive toxicity, reactive oxygen species, possible carcinogen
editFor use in cosmetics, the EWG describes retinyl acetate as a high-risk ingredient, citing data from the FDA and toxicological research: https://www.ewg.org/skindeep/ingredients/705543-RETINYL_ACETATE_(VITAMIN_A_ACETATE)/
- Reactive oxygen species formation: https://www.ncbi.nlm.nih.gov/pubmed/15720116
- Tumor risk: https://www.ncbi.nlm.nih.gov/pubmed/23001333
- Reproductive toxicity - NIH: https://ods.od.nih.gov/factsheets/VitaminA-HealthProfessional/ — Preceding unsigned comment added by 85.208.247.71 (talk) 12:26, 11 March 2020 (UTC)
Natural source
editThe NCI Drug Dictionary calls retinyl acetate "natural", but does not elaborate what natural sources there are. For all I know, animals tend to not make these sort of short-chain esters of retinol (PMID 23625372). --Artoria2e5 🌉 03:01, 16 November 2020 (UTC)