Talk:Succinate dehydrogenase
 | This article is rated C-class on Wikipedia's content assessment scale. It is of interest to the following WikiProjects: | |||||||||||||
| ||||||||||||||
"Research on Succinate-coenzyme Q Reductase Complex"
editThis whole section, except for the "Diseases linked to succinate dehydrogenase include hereditary paraganglioma, obsessive compulsive disorder, generation of aromatic flatulants, and dwarfism. Removal of this enzyme from the genome has also been shown to be embryonic lethal."-part that should be moved to the section "Role in disease", is plain "blah blah blah". - Boris 20:36, 17 January 2007 (UTC)
Subunits and structure
editAlthough the most recent edits are a week ago, the current text looks as if it is in the middle of being edited, since it refers to several figures that are not present, such as figures 4 and 5. The explanation of the structure of subunits appears to be well written, but will only make sense when all the intended figures are present and correctly matched with the text. I look forward to reading this article when whoever was editing it, or another expert, brings it into coherent form.CharlesHBennett (talk) 17:07, 1 April 2013 (UTC) As of August 2018, the reference to the non-existent Figure 4 has still not been resolved.77.147.138.163 (talk) 07:38, 9 August 2018 (UTC)
embryonic lethality
editCurrent text says "The fundamental role of succinate-coenzyme Q reductase in the electron transfer chain of mitochondria makes it vital in most multicellular organisms, removal of this enzyme from the genome has also been shown to be lethal at the embryonic stage in mice." Since Complex I and complex II operate in parallel, it seems possible that the loss of this gene is embryonic lethal not because of its fundamental role in the ETC, but because of its fundamental role in the TCA cycle. Rdphair (talk) 23:07, 13 October 2016 (UTC)
Mitochondrial Complex II
editIt might be beneficial to include "mitochondrial complex II" along with respiratory complex II. I believe that is what SDH is referred to on the "Electron transport chain" wikipedia page. That might help clear up some potential confusion. IamWill (talk) 23:45, 24 January 2017 (UTC)
Electron tunneling
editI believe there are a total of three Fe-S clusters which was not mentioned. Is that indicated by the 3Fe-4S or is that referring to the contents of one of the clusters? IamWill (talk) 23:58, 24 January 2017 (UTC)
Merger
editI support the merger of Succinate dehydrogenase subunit E into Succinate dehydrogenase (as initially proposed by anon 81.236.207.188 (talk · contribs · WHOIS)). If some day there is so much information that each subunit needs its own page then they could be easily split again. T.Shafee(Evo&Evo)talk 09:59, 20 September 2019 (UTC)