Talk:Sucralfate

Wiki Education Foundation-supported course assignment

This article is or was the subject of a Wiki Education Foundation-supported course assignment. Further details are available on the course page. Student editor(s): 133pharm23, Zpallack23, Jackietam23, MeyerC G22. Peer reviewers: Mog22, LeiC CP133 G22, KuangK CP133 G22.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 10:23, 17 January 2022 (UTC)

Image

The prescribing information PDFs at Axcan Pharma contain images that may be suitable for this entry. —Preceding unsigned comment added by 68.192.161.254 (talk) 23:02, 28 September 2007 (UTC)

Added. -- Ed (Edgar181) 23:53, 24 May 2008 (UTC)

Citations

In an effort to improve this article, I request that someone who is familiar with the literature please provide references for the Mechanism of Action section (or anywhere else in the article that makes uncited claims). I have found a few sources, listed below, but am not sure of their quality.

• Mechanisms of action of sucralfate
• The mechanism of protective, therapeutic and prophylactic action of sucralfate
• Mechanisms of gastroduodenal protection by sucralfate

--BBUCommander (talk) 20:19, 30 January 2013 (UTC)

Edit Summary

We focused on improving this article by finding relevant references to support the material. We edited the lead section by making minor grammatical changes and making it more readable (less technical terms). We made minor edits to the Adverse reaction and PK sections. The Medical uses section is very cluttered and may the the target of future revisions. Zpallack23 (talk) 09:04, 5 November 2015 (UTC)

Peer Review

1. Does the article provide a neutral point of view? Yes, the article is neutral throughout.

2. Are the points included verifiable with cited published material? Yes, everything appears well cited, except for the listed brand names in the lead.

3. What recommendations can you provide your colleague for improvement of their draft? In the PK sections, you should link "PUD" to the wikipedia article on PUD, or at least type out what PUD is. Same with "PO", a public reader may not know what that means. In the adverse events section you mention that not many studies with pregnant women have been done, but it may be worth it to include that it is category B. Grammatically, the brand names listed should be separated by commas, not semicolons. Many medical and technical terms are used, would suggest more lay person terms & simplifying descriptions, especially in the medical uses section. Also, be sure to link terms with their appropriate wiki page -- for example, a wiki link to ICRU-CRBED would help the audience understand the content.

-Mog22 (talk) 22:49, 5 November 2015 (UTC)

Article is self-contradictory

Under the medical uses section, the article contains directly contradictory statements about sucralfate's use for gastric ulcers.

In the introductory paragraph, it says

It is not FDA approved for gastric ulcers, as the main mechanism is not due to acid oversecretion but rather from diminished protection.

But then in the list for "other uses," the third listing is for gastric ulcers.

So obviously this needs to be either clarified (if there's some situations where it's used and some where it's not) or resolved one way or the other. I don't have access to or experience with the relevant research, but I'm sure someone out there does. this name is also in use 00:24, 12 June 2016 (UTC)

I just noticed that sentence and thought the same. Since sucralfate has a protective effect (binds to the ulcer), that would seem to be a reason for using it for gastric ulcers. Maybe need to check the FDA docs on it. As far as other uses, it's common for meds to be used for non-FDA approved uses, where it is thought they are effective.JuanTamad (talk) 08:35, 21 January 2018 (UTC)

How can it be synthesised

Since it is a chemical/molecule - What routes are there to its synthesis ? - Rod57 (talk) 20:49, 4 December 2019 (UTC)