Talk:Sulfonamide (medicine)
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If
editIf the terms are interchangeable or if the term 'sulfa' is simply another name for a well-known sulfa-drug, it only seems reasonable to merge it into the main sulfa drug page.
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Picture
editWho has a picture of the structure of sulfonamides? Sikkema 20:47, 30 September 2007 (UTC)
Shouldn't sulfacetamide be added to the list of sulfonamides? Its page says it is one.
Sulfonamide vs. Sulfa drug
editWhy is there a page for "Sulfa drug" if it is basically the same as "Sulfonamide (medicine)" and there talk pages are merged? I'm going to remove "Sulfa drug" and place a redirect in a few days if I don't hear any reason not to.Lizz612 20:10, 9 November 2007 (UTC)
- Actually I'm going to just propose a merger instead. There is information on Sulfa drug that isn't on sulfonamide.Lizz612 16:22, 12 November 2007 (UTC)
- 'Agree' - go for it David Ruben Talk 01:14, 13 November 2007 (UTC)
- Support merge, as mentioned over at WT:PHARM :) Fvasconcellos (t·c) 01:23, 13 November 2007 (UTC)
Okay, I think its mostly merged. I'll clean it up more later then delete and redirect Sulfa drug. It wasn't nearly as hard as I thought it would be. A tabbed browser sure is useful. :) -- Lizz612 (talk) 20:18, 16 November 2007 (UTC)
- All done with the merge and redirect. Probably needs some tiding up as far as possibly redundant info goes.Lizz612 (talk) 17:45, 17 November 2007 (UTC)
Expansion
editCan we get a section that talks about what diseases/situations are treated with sulfa drugs, and compare them to other antibiotics? WhatamIdoing (talk) 05:25, 14 December 2007 (UTC)
History of sulfa drugs
editThe history of sulfa drugs and Gerhard Domagk's role is described in Thomas Hager's book "The Demon Under the Microscope: From Battlefield Hospitals to Nazis Labs, One Doctor's Heroic Search for the World's First Miracle Drug" Leonmartens (talk) 15:51, 10 January 2009 (UTC) "During the years 1942 to 1943, Nazi doctors conducted sulfanilamide experiments on prisoners in concentration camps." I took this out as it is not cited anywhere and seems like propaganda to me. What type of evil sulfanilamide experiments did they conduct? —Preceding unsigned comment added by 99.249.224.142 (talk) 00:28, 17 April 2009 (UTC)
The Nazi experiments on human beings is well documented, starting with the Neurenberg War Crimes Trials: [1] which includes both quotations from the Nuremberg Trials and graphic illstration, or [2] which describes "Oberhauser was telling us that these were great scientific experiments that should solve a number of important questions in the treatment of gun shot wounds and other war injuries, and especially the gangrene and bone transplants.
There were two kinds of experiments. In the first type gangrene, tetanus and staphylococci bacteria were implanted or injected into artificially cut wounds of healthy extremities. This happened in the case of the first five, who were desperately and hysterically screaming and who all died, one of tetanus, two of gangrene, one of blood poisoning, and one bled to death."
or this article on Ravensbruck Concentration Camp [3] which details "They all conducted or participated in various experiments such as sulphanilamide (Sulfonamide), bone, muscle, nerve regeneration, bone transplantation and sterilization experiments."
Is this enough to satisfy your standard of evil? --Commentarius (talk) 19:29, 27 April 2010 (UTC)
Sulfanilamide & PABA structure depiction
editGreat article -- especially the historical perspectives! The sulfanilamide structure doesn't look right. Shouldn't the 'R' be 'NH2'? Compare w/ Wikipedia article "Sulfanilamide". — Preceding unsigned comment added by Dpwkbw (talk • contribs) 20:29, 29 March 2013 (UTC)
February 2009 temple?
editThis article needs additional citations for verification. (February 2009) |
The problem are already solved, why keeping this till 2015?
I guess wiki management is lazy and selfishness
--36.225.99.141 (talk) 11:35, 22 December 2015 (UTC)
Image contradiction: which form of folate is inhibited?
editIn § Antimicrobial, the article says that "folate synthesis" is inhibited, with the image File:Sulfa folate.svg. The caption and (I think) the image structure specify tetrahydrofolate but the in-image caption text, the image-description page on commons, and the captions in several other wikipedia languages' versions of this article say dihydrofolate. Which one is intended here? DMacks (talk) 07:18, 18 February 2019 (UTC)
US usage
edit"Nowadays, while sulfonamides seldom appear in the prescriptions written by doctors in developed countries, sulfonamides are still common antimicrobial medications in developing countries owing to their low price"
As a US emergency medicine doctor, that statement seems quite false. Sulfamethoxazole, as part of Bactrim/ Septra is used all the time in the US for treatment of cMRSA skin infections and UTIs
— Preceding unsigned comment added by 2600:1700:b530:5090:b18d:7d8b:9f4a:c61 (talk) 23:22, 4 May 2019 (UTC)
request
edityour description of history of antibiotic isn't quite in agreement with what is writtern here https://en.wikipedia.org/wiki/Prontosil
can you and the editors of the other article harmonize ? thanks !! — Preceding unsigned comment added by 2601:192:4700:1F70:2819:392F:327A:79D7 (talk) 15:37, 24 December 2021 (UTC)
Repeat in the side effects
editThere is a large section entirely dedicated to this, however the last paragraph is repeating the same information. 90.255.216.196 (talk) 08:54, 7 October 2022 (UTC)