Talk:Synthesis of nucleosides
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The Silyl-Hilbert-Johnson Reaction
editI think there some error on the first reaction with the tri-hydroxybenzen-acetylribose + TMSOTf cause the reaction involves 5 O-atoms int the ribose + one in the TMSOTf but then there are 5 O-atoms on the ribose + the -OTf anion + the TMSOAc leaving. That makes 7 O-atoms. — Preceding unsigned comment added by 128.179.252.50 (talk) 07:26, 2 February 2015 (UTC)
There is a mistake as well in eq. 12. The OBz groups should be removed and "OH" should be written instead. (The NH3/MeOH conditions will cleave the OBz-protecting group). Thanks — Preceding unsigned comment added by 132.230.239.94 (talk) 13:34, 28 December 2015 (UTC)
There are, in fact, many errors in the formulae/equations. Those listed above as well as preservation of the leaving group in equation 2, non-anomeric position reactions later on, etc. If I had access to a proper structure editor, I would fix the issue myself, but as such, it needs someone else to do so... — Preceding unsigned comment added by 132.180.64.92 (talk) 11:52, 30 September 2016 (UTC)
There is a serious mistake in equation (4). The compound at the lower left corner of this scheme has no nucleophilic nitrogens; the intermediate may form, but there's nothing it can do. In addition, everyone one of these structures should be numbered. There's no excuse for this laziness.AWCzarnik (talk) 02:27, 1 October 2022 (UTC)