Talk:Tramadol
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Mix with Benzos
editWhy is there no warning about mixing a narcotic with Benzodiazepines?? Or did I miss it?? Lady Meg (talk) 05:26, 27 July 2023 (UTC)
WADA ban
editTramadol will be banned for all international sport by WADA effective January 1, 2024. I don't have time to find the citation for this but should be easy to verify. 207.180.169.36 (talk) 14:25, 16 October 2023 (UTC)
Mechanism of action
editTramadol is a SYNTHETIC opioid analgesic Kenntex (talk) 02:04, 9 November 2023 (UTC)
"Dependence liability": moderate or low?
editThere have been some edits changing the classification of the "dependence liability" in the drug infobox. I reverted the first, unexplained, edit after cursorily checking the quoted literature, Dunn et al. 2019, and not directly seeing something to back up the change. Now the classification has been changed again. Can someone please point me to the proper section and quote in this paper that the classification should be based on? What I found was: "This review summarized 13 human laboratory studies that empirically examined the abuse potential of tramadol. [...] Overall, the reviewed data provide evidence that tramadol has a risk for abuse, but that its risk is generally lower than most of the opioids to which it was compared." https://pmc.ncbi.nlm.nih.gov/articles/PMC6775208/ Lower is not necessarily low. I suggest that the classification should not be based on this reference at all. Biologos (talk) 14:09, 12 November 2024 (UTC)
- Since the dependence liability is poorly sourced, i.e. with a review of studies investigating the abuse potential in laboratory settings, which does not explicitly mention a classification at all, I will remove this section from the drug box for now and invite everyone to find a good reference to re-add it. Biologos (talk) 13:01, 17 November 2024 (UTC)