Talk:Vaseline/Archives/2016

Latest comment: 8 years ago by Full circ in topic Need cherry flavor for lips in Tx


Trademark vs Generic

Exact list of countries: "Vaseline body lotion, shower gel, deodorant (Vasenol in Portugal, Brazil, Italy, India, Spain and Mexico)" from Wikipedia: List_of_Unilever_brands#Home_and_personal_care_brands.5B7.5D
But "Vaseline and Vasenol products are available in over 90 countries around the world* (Vasenol is the alternative name for Vaseline in Portuguese and Spanish speaking countries)" from Unilever [1]
Discussion of Class 3 goods is unnecessary in Vaseline article and I've simplified. Cgmusselman (talk) 21:02, 23 October 2011 (UTC)

References

It's called [vazelin] in Slavic countries, please. — Preceding unsigned comment added by Kirka80286 (talkcontribs) 12:58, 20 February 2014 (UTC)

Dr. David Morrison - Petrolatum a Useful Classic

Link:http://www.lotioncrafter.com/pdf/Petrolatum_A_Useful_Classic.pdf

This source covers Dr Morrison's research into Petroleum Jellies in the 90's. Along with some historical information about Vaseline and patent history, it covers medical uses, safety, and personal care around Petroleum Jellies. I would think it would be very useful for the "Usage" section on the Vaseline page, which currently has no references. JohnB0207 (talk) 16:22, 15 January 2016 (UTC)

U.S. Food and Drug Administration

In 21CFR Part 347 (55 FR No. 19; June 20, 1990) Skin Protectant Drug Products for OTC Human Use; Proposed Rulemaking for Diaper Rash Drug Products, The FDA considers the role of skin protectant for treatment of Diaper Rash.

Link: http://www.fda.gov/downloads/Drugs/DevelopmentApprovalProcess/DevelopmentResources/Over-the-CounterOTCDrugs/StatusofOTCRulemakings/ucm091669.pdf

Another source, specifically about Diaper rash. The agency states that “because moisture plays a large part in the development of diaper rash irritation, skin protectant ingredients that absorb or adsorb moisture offers a rational approach to the prevention or treatment of diaper rash.” The agency also specifically identifies that “infant perianal skin is afforded significant protection against diaper wetness by the application of a continuous film of petrolatum to the skin in the diaper area.”

JohnB0207 (talk) 16:21, 15 January 2016 (UTC)

Handbook of Non-prescriptive Drugs (9th edition, 1990)

Like the FDA, the American Pharmaceutical Association assessed the roles of skin protectants and skin treatments for diaper rash. They indicate that only recently have controlled clinical studies of many popular treatment products been reported. While products containing Vitamin A and D, cod liver oil or p-chloromercuriphenol have been shown to be effective, the APA unequivocally states “no evidence exists that indicates any of these products is superior to zinc oxide paste or white petrolatum.”

Their conclusion to pharmacists that white petrolatum or zinc oxide paste should recommended as a protectant and as initial treatment for diaper rash.

Diaper Rash Protection Clinical Study - Bell 1967

This study was conducted between May and September, 1967 at the neonatal nursery in Middlesex Hospital, Middletown CT. Thirty-five newborn infants of both sexes were used in the trial. Vaseline Petroleum Jelly was applied in a continuous film over the skin of the entire diaper area. At the next diaper change, skin was tested for adequacy of protection.

Out of 129 trials, with intervals ranging from 2 to 7 hours, there were only 2 instances of failure to provide a continuous protective film against moisture.

A Study of Vaseline Petroleum Jelly in protection of infants against Diaper Wetness - Snell 1969

This study was conducted through Biological Science Laboratories, Foster D. Snell, Inc. A total of 152 infants and young children participated in the trial conducted in the New York Foundling Hospital. Vaseline Petroleum Jelly was applied to the entire diaper area for periods of up to 10 hours (overnight).

From this data, it was concluded that infant skin is afforded significant protection against diaper wetness by the application of a continuous film of VPJ.

Diaper Rash TREATMENT - Grove 1994

This study was conduced at the Skin Study Center (KGL, Inc.) in early 1994. Six infants with mild to moderate diaper rash were enrolled.

Results show that after 3 days, all subjects were improved from baseline with no adverse reactions. It was concluded that both Vaseline Petroleum Jelly was safe and effective for the treatment of diaper rash. JohnB0207 (talk) 16:26, 15 January 2016 (UTC)

Efficacy: Dry Skin Treatment

Source : Albert Kligman, MD; Regression Method for assessing the efficacy of moisturizers; Cosmetics & Toiletries, 93(27), 27-35 (1978)

"When it comes to efficacy, petrolatum is the unrivalled moisturizer. No material in our experience exceeds it in relieving ordinary xerosis.” A useful source regarding petrolatum. JohnB0207 (talk) 16:22, 15 January 2016 (UTC)

Laser Treatment Post-Op

Source: Richard Fitzpatrick, MD; Single Center evaluation of the efficacy of PSR treatment; From Am Soc of Laser Medicine and Surgery; 27th Annual Conference, April 2007; reported Lasers in Surgery and Medicine; Supplement 19.

“Preliminary evaluation of data demonstrated a minimum 28% reduction in physician wrinkle score at 1 month. … Patients randomized to Petrolatum indicated higher satisfaction and improvement (70% vs 40%) scores than did the Biafine group.”

Regarding the uses of petrolatum again. JohnB0207 (talk) 16:23, 15 January 2016 (UTC)

Skin Barrier Recovery

Sources: Ruby Ghadially, MD, Lars Halkier-Sorensen, MD, Peter Elias, MD; Effects of petrolatum on stratum corneum structure and function; J Am Acad Dermatol., 26 (3), 387-396 (Mar 1992)

D. Morrison, Cosm & Toil 111 (1) 59 (1996) (Review article)


Ointments are thought to be occlusive, thereby blocking transcutaneous water loss, trapping water under the skin and delaying barrier recovery. VPJ accelerated, rather than impeded, barrier recovery… ...Moreover, VPJ was present within the interstices at all levels of the SC where it replaced intercellular bilayers.

Barrier Recovery Benefits: The exact occlusivity of PJ is an important feature. A material (e.g. Saran wrap) giving 100% occlusivity/impermeability (preventing 100% of moisture loss) would be detrimental to the SC – they actually impeded barrier recovery. However, the degree of occlusivity of Petrolatum gives effective protective and moisturization while aiding barrier recovery. “When applied to skin that had been damaged by acetone, Petrolatum accelerated the recovery of the skin’s normal barrier properties “ JohnB0207 (talk) 16:22, 15 January 2016 (UTC)

Wound Protection

Source: Walter Reed Army Medical Center, Dept of Dermatology; Infection and Allergy Incidence in Ambulatory Surgery Patients Using White Petrolatum vs. Bacitracin Ointment, A randomized controlled Trial; J Am Med Assc, 276(12),972-977 (Sep 25 1996)

Conclusion: white petrolatum is a safe, effective wound care ointment for ambulatory surgery. In comparison with bacitracin, white petrolatum possesses and equally low infection rate and minimal risk for induction of allergy. JohnB0207 (talk) 16:23, 15 January 2016 (UTC)

Non Comedogenicity / Does not induce acne

Source: Albert M Kligman, MD; Petrolatum is not comedogenic in rabbits or humans: A critical reappraisal of the rabbit ear assay and the concept of “acne cosmetica”; J. Soc. Cosmet Chem., 47, 41-48 (Jan/Feb 1996)

The objective was to find out whether petrolatum, previously reported to be comedogenic in the rabbit ear model would worsen acne.

No evidence of comedogenic potential was found by the follicular biopsy technique. Papulo-pustules significantly decreased. JohnB0207 (talk) 16:21, 15 January 2016 (UTC)

Non Sensitizing / Hypoallergenic

Source:Alesander Fisher, MD; Cutaneous Reactions to Petrolatum; Cutis, Vol 28, 23-24, 31, 57; July 1981

“Petrolatum as a Patch Test Vehicle - Generally it is agreed that petrolatum (USP), also known as Vaseline or yellow soft paraffin, is the best vehicle for most test substances used in patch tests. Petrolatum is non-sensitizing, nonirritating and so occlusive that it is possible to fix the patch test with non-occlusive, nonirritant adhesive tape [to] prevent adhesive reactions from interfering with test readings.”

Source: Human Maximization Assay - Dr. Kays Kaidbey, KGL Labs, Philadelphia, PA Study KGL2859 May 5, 1992

Objective: To determine the contact sensitization potential of Vaseline PJ. Conclusion: Test sample does not posses a detectable sensitization potential JohnB0207 (talk) 16:24, 15 January 2016 (UTC)

Safe to be ingested

Vaseline Petroleum Jelly also meets the FDA requirements set out in 21CFD172.880. This regulation sets provisions for petrolatum as food grade material. Regulation 172.886 describes the stringent analytical procedures for the petroleum wax. This method defines strict UV absorbance limits of acceptability. Petrolatum meeting regulation 172.880 is in fact safe for human consumption.JohnB0207 (talk) 16:26, 15 January 2016 (UTC)

Need cherry flavor for lips in Tx

The regular is available and the cherry used to be available. For many months the cherry flavor can not be found. People are selling it on line for triple the price. Full circ (talk) 01:41, 14 October 2016 (UTC)