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| Pos | Team | Pld | W | D | L | GF | GA | GD | Pts | Qualification |
|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Cruz Azul (C) | 17 | 13 | 2 | 2 | 26 | 11 | +15 | 41 | Qualification for the quarter-finals[a] |
| 2 | América | 17 | 12 | 2 | 3 | 26 | 14 | +12 | 38[b] | |
| 3 | Puebla | 17 | 7 | 7 | 3 | 25 | 14 | +11 | 28 | |
| 4 | Monterrey | 17 | 8 | 4 | 5 | 22 | 13 | +9 | 28 | |
| 5 | Santos Laguna | 17 | 7 | 5 | 5 | 18 | 13 | +5 | 26 | Qualification for the Reclassification[c] |
| 6 | León | 17 | 8 | 2 | 7 | 25 | 23 | +2 | 26 | |
| 7 | Atlas | 17 | 7 | 4 | 6 | 20 | 15 | +5 | 25[b] | |
| 8 | Pachuca | 17 | 6 | 5 | 6 | 20 | 19 | +1 | 23 | |
| 9 | Guadalajara | 17 | 5 | 8 | 4 | 21 | 21 | 0 | 23 | |
| 10 | UANL | 17 | 6 | 5 | 6 | 19 | 20 | −1 | 23 | |
| 11 | Toluca | 17 | 6 | 4 | 7 | 26 | 24 | +2 | 22 | |
| 12 | Querétaro | 17 | 6 | 3 | 8 | 19 | 25 | −6 | 21 | |
| 13 | Mazatlán | 17 | 6 | 3 | 8 | 19 | 26 | −7 | 21 | |
| 14 | Tijuana | 17 | 5 | 5 | 7 | 19 | 21 | −2 | 20 | |
| 15 | UNAM | 17 | 4 | 6 | 7 | 10 | 12 | −2 | 18 | |
| 16 | Juárez | 17 | 4 | 3 | 10 | 13 | 29 | −16 | 15 | |
| 17 | Atlético San Luis | 17 | 3 | 3 | 11 | 20 | 33 | −13 | 12 | Team is last place in the coefficient table. |
| 18 | Necaxa | 17 | 2 | 5 | 10 | 14 | 29 | −15 | 11 |
Source: Liga MX
Rules for classification: 1) Points; 2) Goal difference; 3) Number of goals scored; 4) Number of goals scored away; 5) Head-to-head results between tied teams; 6) Highest relegation coefficient; 7) Fair Play points
(C) Champions
Notes:
Rules for classification: 1) Points; 2) Goal difference; 3) Number of goals scored; 4) Number of goals scored away; 5) Head-to-head results between tied teams; 6) Highest relegation coefficient; 7) Fair Play points
(C) Champions
Notes:
- ^ The first four places in the table qualified for the Liguilla quarter-finals.
- ^ a b América was penalized for having an ineligible player on the bench in their Week 7 match against Atlas. América originally won the match 0–2 but were docked the 3 points obtained for the victory. Atlas were given a 3–0 victory and the 3 points docked from América.[1]
- ^ Teams ranked 5th to 12th in the table qualified for Reclassification
- ^ "Resolución de la Comisión Disciplinaria". ligamx.net. 22 February 2021.