Template:Infobox drug/testcases-FDA

/sandbox2
Clinical data
License data	US DailyMed: Acetylsalicylic_acid; US FDA: Aspirin;
../licence/sandbox
License data	US DailyMed: Acetylsalicylic_acid; US FDA: Aspirin;

Infobox drug/testcases-FDA
Clinical data
Trade names	Bayer Aspirin, others
Other names	2-acetoxybenzoic acid; o-acetylsalicylic acid; acetylsalicylic acid; acetyl salicylate;
AHFS/Drugs.com	Monograph
MedlinePlus	a682878
License data	EU EMA: by INN; US DailyMed: Acetylsalicylic_acid; US FDA: Aspirin;
Pregnancy; category	AU: C; ;
ATC code	A01AD05 (WHO) B01AC06 (WHO), N02BA01 (WHO);
Legal status
Legal status	AU: OTC / Schedule 2, 4, 5, 6; UK: General sales list (GSL, OTC); US: OTC / Rx-only;
Identifiers
	IUPAC name 2-acetyloxybenzoic acid;
CAS Number	50-78-2;
PubChem CID	2244;
IUPHAR/BPS	4139;
DrugBank	DB00945;
ChemSpider	2157;
UNII	R16CO5Y76E;
KEGG	D00109; C01405;
ChEBI	CHEBI:15365;
ChEMBL	ChEMBL25;
PDB ligand	AIN (PDBe, RCSB PDB);
Chemical and physical data
Formula	C9H8O4
Molar mass	180.159 g·mol−1

Infobox drug/testcases-FDA
Clinical data
Trade names	Bayer Aspirin, others
Other names	2-acetoxybenzoic acid; o-acetylsalicylic acid; acetylsalicylic acid; acetyl salicylate;
AHFS/Drugs.com	Monograph
MedlinePlus	a682878
License data	EU EMA: by INN; US DailyMed: Acetylsalicylic_acid; US FDA: Aspirin;
Pregnancy; category	AU: C; ;
ATC code	A01AD05 (WHO) B01AC06 (WHO), N02BA01 (WHO);
Legal status
Legal status	AU: OTC / Schedule 2, 4, 5, 6; UK: General sales list (GSL, OTC); US: OTC / Rx-only;
Identifiers
	IUPAC name 2-acetyloxybenzoic acid;
CAS Number	50-78-2;
PubChem CID	2244;
IUPHAR/BPS	4139;
DrugBank	DB00945;
ChemSpider	2157;
UNII	R16CO5Y76E;
KEGG	D00109; C01405;
ChEBI	CHEBI:15365;
ChEMBL	ChEMBL25;
PDB ligand	AIN (PDBe, RCSB PDB);
Chemical and physical data
Formula	C9H8O4
Molar mass	180.159 g·mol−1

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aspirin

reduced, as of 08:06, 23 March 2023 (UTC)

Side by side comparison

from article, ref name=b92:

Aspirin, an acetyl derivative of salicylic acid, is a white, crystalline, weakly acidic substance, which melts at 136 °C (277 °F),^[5] :

/sandbox2

{{Infobox drug/sandbox2}} - live code as of 08:42, 23 March 2023 (UTC)

aspirin (complete)

as of 08:06, 23 March 2023 (UTC)

Side by side comparison

Infobox drug/testcases-FDA
Clinical data


Pronunciation	acetylsalicylic acid /əˌsiːtəlˌsælɪˈsɪlɪk/
Trade names	Bayer Aspirin, others
Other names	2-acetoxybenzoic acid o-acetylsalicylic acid acetylsalicylic acid acetyl salicylate
AHFS/Drugs.com	Monograph
MedlinePlus	a682878
License data	EU EMA: by INN US DailyMed: Acetylsalicylic_acid US FDA: Aspirin
Pregnancy category	AU: C^[1]
Routes of administration	By mouth, rectal
ATC code	A01AD05 (WHO) B01AC06 (WHO), N02BA01 (WHO)
Legal status
Legal status	AU: OTC / Schedule 2, 4, 5, 6^[6]^[7] UK: General sales list (GSL, OTC) US: OTC / Rx-only
Pharmacokinetic data
Bioavailability	80–100%^[8]
Protein binding	80–90%^[9]
Metabolism	Liver (CYP2C19 and possibly CYP3A), some is also hydrolysed to salicylate in the gut wall.^[9]
Elimination half-life	Dose-dependent; 2–3 h for low doses (100 mg or less), 15–30 h for large doses.^[9]
Excretion	Urine (80–100%), sweat, saliva, feces^[8]
Identifiers
IUPAC name 2-acetyloxybenzoic acid^[10]
CAS Number	50-78-2^Y
PubChem CID	2244
IUPHAR/BPS	4139
DrugBank	DB00945^Y
ChemSpider	2157^Y
UNII	R16CO5Y76E
KEGG	D00109^Y C01405^Y
ChEBI	CHEBI:15365^Y
ChEMBL	ChEMBL25^Y
PDB ligand	AIN (PDBe, RCSB PDB)
Chemical and physical data
Formula	C₉H₈O₄
Molar mass	180.159 g·mol⁻¹
3D model (JSmol)	Interactive image
Density	1.40 g/cm³
Melting point	136 °C (277 °F) ^[5]
Boiling point	140 °C (284 °F) (decomposes)
Solubility in water	3 g/L
SMILES O=C(C)Oc1ccccc1C(=O)O
InChI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)^Y Key:BSYNRYMUTXBXSQ-UHFFFAOYSA-N^Y
(verify)

Infobox drug/testcases-FDA
Clinical data


Pronunciation	acetylsalicylic acid /əˌsiːtəlˌsælɪˈsɪlɪk/
Trade names	Bayer Aspirin, others
Other names	2-acetoxybenzoic acid o-acetylsalicylic acid acetylsalicylic acid acetyl salicylate
AHFS/Drugs.com	Monograph
MedlinePlus	a682878
License data	EU EMA: by INN US DailyMed: Acetylsalicylic_acid US FDA: Aspirin
Pregnancy category	AU: C^[1]
Routes of administration	By mouth, rectal
ATC code	A01AD05 (WHO) B01AC06 (WHO), N02BA01 (WHO)
Legal status
Legal status	AU: OTC / Schedule 2, 4, 5, 6^[6]^[7] UK: General sales list (GSL, OTC) US: OTC / Rx-only
Pharmacokinetic data
Bioavailability	80–100%^[8]
Protein binding	80–90%^[9]
Metabolism	Liver (CYP2C19 and possibly CYP3A), some is also hydrolysed to salicylate in the gut wall.^[9]
Elimination half-life	Dose-dependent; 2–3 h for low doses (100 mg or less), 15–30 h for large doses.^[9]
Excretion	Urine (80–100%), sweat, saliva, feces^[8]
Identifiers
IUPAC name 2-acetyloxybenzoic acid^[10]
CAS Number	50-78-2^Y
PubChem CID	2244
IUPHAR/BPS	4139
DrugBank	DB00945^Y
ChemSpider	2157^Y
UNII	R16CO5Y76E
KEGG	D00109^Y C01405^Y
ChEBI	CHEBI:15365^Y
ChEMBL	ChEMBL25^Y
PDB ligand	AIN (PDBe, RCSB PDB)
Chemical and physical data
Formula	C₉H₈O₄
Molar mass	180.159 g·mol⁻¹
3D model (JSmol)	Interactive image
Density	1.40 g/cm³
Melting point	136 °C (277 °F) ^[5]
Boiling point	140 °C (284 °F) (decomposes)
Solubility in water	3 g/L
SMILES O=C(C)Oc1ccccc1C(=O)O
InChI InChI=1S/C9H8O4/c1-6(10)13-8-5-3-2-4-7(8)9(11)12/h2-5H,1H3,(H,11,12)^Y Key:BSYNRYMUTXBXSQ-UHFFFAOYSA-N^Y
(verify)

from article, ref name=b92:

Aspirin, an acetyl derivative of salicylic acid, is a white, crystalline, weakly acidic substance, which melts at 136 °C (277 °F),^[5] :

^ ^a ^b "Aspirin Use During Pregnancy". Drugs.com. 2 April 2018. Retrieved 29 December 2019.
^ https://www.tga.gov.au/resources/publication/publications/otc-medicine-monograph-aspirin-tablets-oral-use
^ "Poisons Standard October 2022". Australian Government Federal Register of Legislation. Retrieved 9 January 2023.
^ CID 2244 from PubChem
^ ^a ^b ^c Haynes, William M., ed. (2011). CRC Handbook of Chemistry and Physics (92nd ed.). Boca Raton, FL: CRC Press. p. 3.8. ISBN 1-4398-5511-0.
^ https://www.tga.gov.au/resources/publication/publications/otc-medicine-monograph-aspirin-tablets-oral-use
^ "Poisons Standard October 2022". Australian Government Federal Register of Legislation. Retrieved 9 January 2023.
^ ^a ^b "Zorprin, Bayer Buffered Aspirin (aspirin) dosing, indications, interactions, adverse effects, and more". Medscape Reference. WebMD. Archived from the original on 7 April 2014. Retrieved 3 April 2014.
^ ^a ^b ^c Brayfield A, ed. (14 January 2014). "Aspirin". Martindale: The Complete Drug Reference. Pharmaceutical Press. Retrieved 3 April 2014.
^ CID 2244 from PubChem

[Drugs.com_Pregnancy-1] "Aspirin Use During Pregnancy". Drugs.com. 2 April 2018. Retrieved 29 December 2019.

[2] ttps://www.tga.gov.au/resources/publication/publications/otc-medicine-monograph-aspirin-tablets-oral-use

[3] "Poisons Standard October 2022". Australian Government Federal Register of Legislation. Retrieved 9 January 2023.

[4] CID 2244 from PubChem

[b92-5] Haynes, William M., ed. (2011). CRC Handbook of Chemistry and Physics (92nd ed.). Boca Raton, FL: CRC Press. p. 3.8. ISBN 1-4398-5511-0.

[6] ttps://www.tga.gov.au/resources/publication/publications/otc-medicine-monograph-aspirin-tablets-oral-use

[7] "Poisons Standard October 2022". Australian Government Federal Register of Legislation. Retrieved 9 January 2023.

[MSR-8] "Zorprin, Bayer Buffered Aspirin (aspirin) dosing, indications, interactions, adverse effects, and more". Medscape Reference. WebMD. Archived from the original on 7 April 2014. Retrieved 3 April 2014.

[MD-9] Brayfield A, ed. (14 January 2014). "Aspirin". Martindale: The Complete Drug Reference. Pharmaceutical Press. Retrieved 3 April 2014.

[10] CID 2244 from PubChem

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Clinical data
License data	US DailyMed: Acetylsalicylic_acid US FDA: Aspirin
../licence/sandbox
License data	US DailyMed: Acetylsalicylic_acid US FDA: Aspirin