Beta-2 adrenergic receptor
editInverse agonists "N/A"
editBeta-2 adrenergic receptor | |
---|---|
Transduction mechanisms | Primary: Gs Secondary: Gi/o |
Primary endogenous agonists | epinephrine, norepinephrine |
Agonists | isoprenaline, salbutamol, salmeterol, etc. |
Antagonists | carvedilol, propranolol, labetalol, etc. |
Inverse agonists | N/A |
Positive allosteric modulators | Zn2+ (low concentrations) |
Negative allosteric modulators | Zn2+ (high concentrations) |
External resources | |
IUPHAR/BPS | 29 |
DrugBank | P07550 |
HMDB | HMDBP01634 |
Inverse agonists undefined
editBeta-2 adrenergic receptor | |
---|---|
Transduction mechanisms | Primary: Gs Secondary: Gi/o |
Primary endogenous agonists | epinephrine, norepinephrine |
Agonists | isoprenaline, salbutamol, salmeterol, etc. |
Antagonists | carvedilol, propranolol, labetalol, etc. |
Positive allosteric modulators | Zn2+ (low concentrations) |
Negative allosteric modulators | Zn2+ (high concentrations) |
External resources | |
IUPHAR/BPS | 29 |
DrugBank | P07550 |
HMDB | HMDBP01634 |
Inverse agonists parameter missing
editBeta-2 adrenergic receptor | |
---|---|
Transduction mechanisms | Primary: Gs Secondary: Gi/o |
Primary endogenous agonists | epinephrine, norepinephrine |
Agonists | isoprenaline, salbutamol, salmeterol, etc. |
Antagonists | carvedilol, propranolol, labetalol, etc. |
Positive allosteric modulators | Zn2+ (low concentrations) |
Negative allosteric modulators | Zn2+ (high concentrations) |
External resources | |
IUPHAR/BPS | 29 |
DrugBank | P07550 |
HMDB | HMDBP01634 |
TAAR1
editAntagonists parameter "None characterized", inverse agonists listed
editTrace amine-associated receptor 1 | |
---|---|
Transduction mechanisms | Gs, Gq, GIRKs, β-arrestin 2 |
Primary endogenous agonists | tyramine, β-phenylethylamine, octopamine, dopamine |
Agonists | Endogenous: trace amines Exogenous: RO5166017, amphetamine, methamphetamine, others |
Neutral antagonists | None characterized |
Inverse agonists | EPPTB |
Positive allosteric modulators | N/A |
Negative allosteric modulators | N/A |
External resources | |
IUPHAR/BPS | 364 |
DrugBank | Q96RJ0 |
HMDB | HMDBP10805 |
Antagonists parameter "N/A"
editTrace amine-associated receptor 1 | |
---|---|
Transduction mechanisms | Gs, Gq, GIRKs, β-arrestin 2 |
Primary endogenous agonists | tyramine, β-phenylethylamine, octopamine, dopamine |
Agonists | Endogenous: trace amines Exogenous: RO5166017, amphetamine, methamphetamine, others |
Neutral antagonists | N/A |
Inverse agonists | EPPTB |
Positive allosteric modulators | N/A |
Negative allosteric modulators | N/A |
External resources | |
IUPHAR/BPS | 364 |
DrugBank | Q96RJ0 |
HMDB | HMDBP10805 |
Inverse agonists parameter undefined
editTrace amine-associated receptor 1 | |
---|---|
Transduction mechanisms | Gs, Gq, GIRKs, β-arrestin 2 |
Primary endogenous agonists | tyramine, β-phenylethylamine, octopamine, dopamine |
Agonists | Endogenous: trace amines Exogenous: RO5166017, amphetamine, methamphetamine, others |
Antagonists | None characterized |
Positive allosteric modulators | N/A |
Negative allosteric modulators | N/A |
External resources | |
IUPHAR/BPS | 364 |
DrugBank | Q96RJ0 |
HMDB | HMDBP10805 |